Senior Scientist, Bioprocess Development & Scale-Up

Boston Postdoctoral Association; Boston (MA); Presencial; USD 120.000 - 190.000; Jornada completa

Descripción de la vacante

Kano Therapeutics, a biotech startup focused on DNA nanotechnology, seeks a Scientist/Senior Scientist, Process Development - Microbiology. You will lead design and scale-up of bacterial fermentation and downstream processing for therapeutic products, transitioning from research batches to clinical-grade production.

You will drive in-line QC assays, develop process safety plans, and build scalable manufacturing workflows, with emphasis on upstream/downstream integration and cost/quality metrics.

Formación

• Ph.D. in related field OR 5+ years of industry experience.
• Experience with recombinant protein production and purification.
• Skilled in microbiology and fermentation engineering, including upstream and downstream process development e.g. TFF, LC.
• Demonstrated abilities in process safety management, including process hazards analysis and mitigation.

Responsabilidades

• Design, build, and test innovative bacterial fermentation and downstream processing platform for therapeutic products.
• Create and execute on experimental workflows, set up in-line quality control assays, industrial process development from automated small-scale to scaled solution.
• Creation of quality management plan including metrics for monitoring process control.

Conocimientos

Bioprocessing

Fermentation eng

Microbiology

Process safety

Educación

Ph.D. in related field

Herramientas

TFF

LC

Descripción del empleo

Kano Therapeutics, a biotech startup focused on DNA nanotechnology, seeks a Scientist/Senior Scientist, Process Development - Microbiology. You will lead design and scale-up of bacterial fermentation and downstream processing for therapeutic products, transitioning from research batches to clinical-grade production.

You will drive in-line QC assays, develop process safety plans, and build scalable manufacturing workflows, with emphasis on upstream/downstream integration and cost/quality metrics.