Upstream Process Scientist, Mammalian Culture & Scale-Up

Scorpion Therapeutics; Spring House (PA); On-site; USD 90,000 - 150,000; Full time

Job summary

Scorpion Therapeutics in Spring House, PA is seeking an Upstream Process Development Scientist to scale cell culture processes for in vivo biologics and gene therapies. You will design and execute development studies across shake flasks, bioreactors, and high-throughput platforms, and optimize fed-batch and perfusion strategies.

The role requires hands-on bioreactor operation, proficiency with Ambr 250 systems, and strong data analytics using JMP, MiniTab or Python to drive process understanding

Qualifications

• BS/MS in Chemical/Biochemical Engineering, Biological Sciences, or related field.
• 2–4+ years’ experience in mammalian cell culture process development.
• Hands-on bioreactor operation and scale-up experience.

Responsibilities

• Design and execute development studies using shake flasks, bioreactors, and high-throughput systems.
• Optimize fed-batch and perfusion processes for mammalian cells.
• Utilize Ambr 250 bioreactors in development work.
• Apply statistical design and data analytics to enable process understanding.
• Support evaluation of novel technology and cross-functional collaboration.
• Author technical and regulatory documentation.

Skills

Bioreactor ops

Cell culture

Data analysis

Python

Ambr 250

Education

BS/MS in relevant field

Tools

JMP

MiniTab

Job description

Scorpion Therapeutics in Spring House, PA is seeking an Upstream Process Development Scientist to scale cell culture processes for in vivo biologics and gene therapies. You will design and execute development studies across shake flasks, bioreactors, and high-throughput platforms, and optimize fed-batch and perfusion strategies.

The role requires hands-on bioreactor operation, proficiency with Ambr 250 systems, and strong data analytics using JMP, MiniTab or Python to drive process understanding