Senior Scientist, Antibody RepSeq Discovery & ML Insight

Allergan

Worcester (MA)

On-site

USD 120,000 - 180,000

Full time

14 days+
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Job summary

AbbVie Bioresearch Center in Worcester, MA, seeks a Senior Scientist to lead antibody repertoire sequencing efforts and expand RepSeq capabilities for therapeutic discovery in immunology, oncology and neurology.

The role blends wet-lab and computational work, collaborating with data scientists to advance RepSeq analyses for immunology, neurology and oncology programs in a fast-paced, matrixed team.

Qualifications

  • PhD or MS/BS with extensive experience in immunology and antibody biology
  • Experience with germline genes, V(D)J recombination and SHM
  • NGS technologies and platforms including Illumina NextSeq/MiSeq and PacBio
  • Molecular biology skills: PCR, cloning, Gibson Assembly
  • Ability to streamline processes and maintain documentation
  • Excellent communication in a matrixed team

Responsibilities

  • Act as expert in RepSeq for therapeutic antibody discovery
  • Collaborate with computational scientists to optimize repertoire analysis
  • Generate, document and archive repertoire data with metadata
  • Analyze results and present at team meetings
  • Coordinate work across a matrixed project team
  • Demonstrate scientific excellence across multiple projects
  • Demonstrate strong interpersonal and communication skills

Skills

Immunoglobulin genetics
RepSeq
Computational biology
Molecular biology
Data analysis
Cross-functional collaboration

Education

PhD in immunology or related
MS in biology or bioinformatics
BS in related field

Tools

PipeBio
Geneious
Sequencher
MS Office

Job description

AbbVie Bioresearch Center in Worcester, MA, seeks a Senior Scientist to lead antibody repertoire sequencing efforts and expand RepSeq capabilities for therapeutic discovery in immunology, oncology and neurology.

The role blends wet-lab and computational work, collaborating with data scientists to advance RepSeq analyses for immunology, neurology and oncology programs in a fast-paced, matrixed team.

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