Senior Quantitative Systems Pharmacology Lead

Socket.dev; Upper Providence (Delaware County); On-site; USD 158,000 - 263,000; Full time

Benefits offered by this job

Health care benefits

Retirement benefits

Paid holidays

Vacation

Paid caregiver/parental leave

Paid medical leave

Job summary

GSK is seeking an Associate Director, Quantitative Systems Pharmacology Disease Lead to develop and apply QSP models within DMPK, guiding target prioritization and modality evaluation. You will integrate data across disciplines and influence drug disposition insights to accelerate clinical translation.

The role requires a PhD in a quantitative field and 2+ years in pharma, with expertise in MATLAB/SimBiology/Python and state-of-the-art modeling techniques across complex biological pathways.

Qualifications

• We require a PhD in a quantitative field with PhD-level modeling experience.
• 2+ years in Pharma/Life Science applying QSP to discovery or development.
• Strong background in mathematical modeling, statistics, and numerical methods.
• Experience with modeling and simulation tools and programming languages.

Responsibilities

• Build and apply QSP models of biological and disease processes.
• Collaborate with biologists, clinicians, and modelers to inform programs.
• Lead as disease-area QSP expert in pathophysiology and endpoints.
• Serve as QSP modeling contact on project teams and interpret data.
• Develop mathematical tools to link system-level and drug-level responses.
• Analyze complex datasets in disease mechanisms and pathways.
• Explore combining QSP with AI/ML and omics data.
• Perform verification and validation of QSP models and outputs.

Skills

Artificial Intelligence

Computational Sciences

Computer Programming

Data Analysis

Data Management

Data Modeling

Data Science

Predictive Modeling

Statistical Models

Education

PhD in Applied Mathematics

Engineering

Pharmaceutical Sciences

Systems Biology

Tools

MATLAB

SimBiology

Julia

Python

C/C++

Job description

GSK is seeking an Associate Director, Quantitative Systems Pharmacology Disease Lead to develop and apply QSP models within DMPK, guiding target prioritization and modality evaluation. You will integrate data across disciplines and influence drug disposition insights to accelerate clinical translation.

The role requires a PhD in a quantitative field and 2+ years in pharma, with expertise in MATLAB/SimBiology/Python and state-of-the-art modeling techniques across complex biological pathways.