Senior Protein Purification Scientist - Biopharma

Systimmune; Bothell (WA); On-site; USD 70,000 - 90,000; Full time

Benefits offered by this job

Comprehensive benefits

401(k) plan with company match

Job summary

SystImmune in Bothell, WA is seeking a Research Associate II or Senior Research Associate to support downstream protein purification, characterization, and process development for preclinical and clinical candidates.

You will report to a Downstream lead, operate ÄKTA systems, perform purifications and analytical assays, and contribute to tech transfer to GMP manufacturing while occasionally working outside normal hours.

Qualifications

• MS or BS in Protein Science, Chemical Engineering, Biochemistry or related field.
• 2+ years industry experience for Research Associate II; BS with 5+ years or MS with 3+ years for Senior.
• Experience with protein chromatography and filtration methods.
• Ability to execute SOPs and biophysical assays for process development.

Responsibilities

• Assist in downstream process development of molecules in pre-clinical and clinical pipelines.
• Perform routine purifications and analytical assays to support cell-line development, upstream, analytical, and formulation groups.
• Execute development experiments to produce scalable and robust purification processes (affinity chromatography, IEX, HIC, CHT) and viral inactivation/filtration processes.
• Generate low endotoxin production runs for pre-clinical studies.
• Compile, analyze, and report data for process development and tech transfer documents.
• Author SOPs for biophysical assays and workflows.
• Participate in timeline planning.

Skills

Protein science background

Biopharmaceutical industry experience

Downstream process development

Education

MS or BS in Protein Science, Chemical Engineering, Biochemistry or related field

Tools

ÄKTA Protein Purification Systems

Unicorn software

SEC-HPLC/UPLC

Tangential Flow Filtration

Viral inactivation/filtration methods

Job description

SystImmune in Bothell, WA is seeking a Research Associate II or Senior Research Associate to support downstream protein purification, characterization, and process development for preclinical and clinical candidates.

You will report to a Downstream lead, operate ÄKTA systems, perform purifications and analytical assays, and contribute to tech transfer to GMP manufacturing while occasionally working outside normal hours.