High-Throughput Antibody & Protein Sciences Associate

Immunomeinc; Bothell (WA); On-site; USD 87,143 - 102,002; Full time

Job summary

Immunome, Inc. is seeking an Associate Scientist, Antibody Sciences to drive in-house high-throughput recombinant protein production, including expression, purification and characterization to support protein engineering and discovery workflows.

The role will leverage SEC-UPLC, HIC-UPLC, DLS, reduced mass spectrometry, and BLI to profile molecules and inform iterative design. You will maintain antibody and protein inventory across the R&D team in Washington state.

Qualifications

• Bachelor’s degree in molecular biology, biochemistry, biophysics, immunology, or related fields.
• 3 years of lab experience in preclinical drug development in biotechnology or pharmaceutical industry, or equivalent.
• Strong understanding of molecular biology and protein sciences.
• Experience with mammalian tissue culture.
• Experience with Octet or similar instrument is a plus.
• Experience with antibody discovery workflows is a plus.
• Familiarity with Benchling is a plus.

Responsibilities

• Recombinant protein production, including high-throughput transient expression and purification.
• Execute analytical assays including SEC-UPLC, HIC-UPLC, DLS, and reduced mass spectrometry.
• Perform mammalian tissue culture in support of recombinant protein production.
• Perform BLI-based assays, including single-point (yes/no) binding and full kinetic binding.
• Maintain strong attention to detail and record keeping for inventory management of recombinant proteins.
• Apply understanding of molecular biology and protein structure, including principles relevant to antibodies.
• Analyze and summarize experimental data from protein production, characterization, and binding assays.
• Collaborate with colleagues across biology, chemistry, pharmacology, and translational medicine to achieve project goals.
• Organize and share data to enable efficient collaboration with other research teams.
• Maintain detailed and accurate electronic laboratory notebooks documenting experimental procedures, results, and conclusions.
• Prepare and present research findings to internal teams and contribute to project updates and strategic discussions.
• Stay informed about the latest advancements in techniques for producing and characterizing protein therapeutics.
• Proactively seek opportunities for professional development and contribute to the scientific growth of the research team.

Skills

Protein expression

Protein purification

Mammalian culture

BLI/Octet

Mass spectrometry

SEC-UPLC

HIC-UPLC

Data analysis

Inventory management

Education

Bachelor's degree in molecular biology/biochemistry/biophysics/immunology

Tools

Octet

Benchling

Job description

Immunome, Inc. is seeking an Associate Scientist, Antibody Sciences to drive in-house high-throughput recombinant protein production, including expression, purification and characterization to support protein engineering and discovery workflows.

The role will leverage SEC-UPLC, HIC-UPLC, DLS, reduced mass spectrometry, and BLI to profile molecules and inform iterative design. You will maintain antibody and protein inventory across the R&D team in Washington state.