Senior Process Engineer, Small Molecule API Manufacturing

BioSpace; Lebanon (IN); On-site; USD 66,000 - 172,000; Full time

Benefits offered by this job

Company bonus

Comprehensive benefits

401(k) and pension

Job summary

Lilly is seeking a small molecule Process Engineer to support a new Lebanon, Indiana pilot plant startup focused on API synthesis. You will develop and sustain process knowledge, optimize operations, and ensure equipment readiness for GMP manufacturing.

The role requires strong technical capabilities, collaboration with multiple teams, and a commitment to quality and safety in a fast-paced environment. Initial locations include Indianapolis/Carmel with a permanent Lebanon site.

Qualifications

• BS or MS in Chemical Engineering or related discipline.
• Minimum of 4 years of experience in pharmaceutical, biotech, chemical manufacturing, or CMO environment or other relevant batch manufacturing process.
• Authorized to work in the United States on a full‑time basis; Lilly will not sponsor work authorization or visas.

Responsibilities

• Perform impact and risk assessments for unit operations.
• Learn the lab and plant design for reactors including automation recipes and procedures.
• Ensure that people and their environment are safe and that company policies concerning safety are followed.
• Ensure processing equipment remains compliant with internal Quality System requirements, applicable engineering standards, and cGMP requirements.
• Assesses rig fit by receiving the technical data package for new processes and performing modeling, simulations and/or experimental work as required to ensure heat and mass transfer are acceptable when scaling to the plant.
• Active engagement and communication with HSE, Quality Assurance, Tech Services, Development, Operations, FUME/C&Q, Automation, Maintenance, Environmental Monitoring, and Manufacturing.
• Author, review, or approve high‑quality technical reports and regulatory submissions dealing with the work performed by the department.
• Demonstrate engagement and employ a quality mindset in all endeavors by proactively identifying quality issues and communicating appropriately.
• Develop or review plans and timetables for project work.

Skills

Analytical skills

Problem-solving

Teamwork

Communication skills

Education

BS or MS in Chemical Engineering

Tools

DeltaV

Dynochem

Aspen

ELN

Job description

Lilly is seeking a small molecule Process Engineer to support a new Lebanon, Indiana pilot plant startup focused on API synthesis. You will develop and sustain process knowledge, optimize operations, and ensure equipment readiness for GMP manufacturing.

The role requires strong technical capabilities, collaboration with multiple teams, and a commitment to quality and safety in a fast-paced environment. Initial locations include Indianapolis/Carmel with a permanent Lebanon site.