Senior MS Translational Scientist & Biomarker Lead

Genentech, Inc.; South San Francisco (CA); On-site; USD 121,000 - 224,000; Full time

Job summary

Genentech, Inc. is seeking a senior scientist-level leader to advance biomarker and translational research in multiple sclerosis within the TM-OMNI program.

The role focuses on identifying novel biomarkers, supporting clinical trials, and guiding biomarker-driven decisions in drug development. The position requires a PhD in Neuroscience and/or Immunology with post-doctoral experience, strong leadership, and the ability to collaborate across global teams.

Qualifications

• PhD in Neuroscience and/or Immunology with post-doctoral experience in translational research or drug development.
• Strong independent research track record and ability to mentor others.
• Excellent writing and communication skills with publications or regulatory reports.

Responsibilities

• Identify new targets and biomarkers to support MS drug development.
• Lead data generation and analyses in internal studies or external collaborations.
• Integrate biomarker data into clinical trial programs to inform pathogenesis and treatment strategies.
• Collaborate across Research, Bioanalytical, Clinical, Biostatistics and Regulatory teams and with external partners.

Skills

Independent thinking

Mentorship

Writing

Communication

Cross-functional collaboration

Hypothesis development

Computational analysis

Lab leadership

Education

PhD in Neuroscience and/or Immunology

Tools

Immunoassay

qPCR

Complex in vitro models

Functional genomics

Genomic sequencing

scRNA-seq

TCR-seq

CITE-seq

Spatial transcriptomics

R

Job description

Genentech, Inc. is seeking a senior scientist-level leader to advance biomarker and translational research in multiple sclerosis within the TM-OMNI program.

The role focuses on identifying novel biomarkers, supporting clinical trials, and guiding biomarker-driven decisions in drug development. The position requires a PhD in Neuroscience and/or Immunology with post-doctoral experience, strong leadership, and the ability to collaborate across global teams.