Biomarker Scientist - Translational Medicine & Omics

F. Hoffmann-La Roche AG; South San Francisco (CA); On-site; USD 100,000 - 186,000; Full time

Job summary

Genentech’s Translational Medicine OMNI team is seeking a Scientist 3 to join on-site at the South San Francisco campus. You will work at the intersection of data science and wet lab, developing biomarkers and assays while analyzing -Omics data to inform CVM programs across drug development stages.

The ideal candidate holds a PhD in Biological Sciences with 0–6 years of wet lab and bioinformatics experience, including R/Python programming, and will contribute to high‑impact publications,

Qualifications

• A PhD in Biological Sciences and 0-6 years of experience in a post‑doc or industry setting with wet lab and bioinformatics experience demonstrated in high‑impact publications.
• Experience in human/clinical research or metabolism is a plus but not required.
• Experience with sample collection/processing and cellular/molecular lab techniques such as cell culture, tissue isolation, immunostaining, molecular biology, ELISA, western blot, sequencing, qRT-PCR, and/or transcriptomics is required.
• Programming experience (R or Python) to run differential expression pipelines and pathway enrichment analyses and to generate figures.
• Ability to develop hypotheses, design experiments, interpret and present results; strong written and oral communication; collaborative teamwork.

Responsibilities

• Establish and conduct experiments with disease‑relevant in‑vitro human cell models.
• Develop, qualify, and validate custom assays (e.g., ELISA, Simoa, NULISA) to support translational research and pipeline programs.
• Analyze -Omics datasets (proteomics, metabolomics, RNAseq) from clinical/preclinical samples to discover biomarkers and targets.
• Communicate findings through reports, publications, and presentations.
• Collaborate with gRED departments and external partners.

Skills

R or Python

Bioinformatics

Communication

Teamwork

Education

PhD in Biological Sciences

Tools

ELISA

Western blot

Genomic sequencing

qRT-PCR

Transcriptomics

Job description

Genentech’s Translational Medicine OMNI team is seeking a Scientist 3 to join on-site at the South San Francisco campus. You will work at the intersection of data science and wet lab, developing biomarkers and assays while analyzing -Omics data to inform CVM programs across drug development stages.

The ideal candidate holds a PhD in Biological Sciences with 0–6 years of wet lab and bioinformatics experience, including R/Python programming, and will contribute to high‑impact publications,