Senior LC-MS Metabolomics Scientist

Yale University; New Haven (CT); On-site; USD 68,000 - 121,000; Full time

Job summary

The Yale University Chemical Metabolism Core in New Haven seeks an experienced analytical chemist/mass spectrometrist to develop and validate LC‑MS/MS assays, perform stable isotope tracing, and support metabolomics, lipidomics, and targeted quantitation across diverse research projects.

The role is bench‑based in a shared core facility, with responsibilities including method development, data processing, QC, and training users, while maintaining detailed records for reproducibility.

Qualifications

• Bachelor’s degree in Chemistry or related field with four years of related experience.
• Experience with LC–MS methods, isotope tracing, and metabolomics/lipidomics is required.
• Ability to communicate results clearly and train users.

Responsibilities

• User Training: Provide advanced training to core users.
• Experiment Support: Design and execute LC‑MS experiments and troubleshoot.
• Facility/Instrument Support: Manage core instrument operations and QC.
• Technique Development: Develop SOPs and optimize analytical methods.

Skills

LC-MS/MS

Mass spectrometry

Stable isotope tracing

Metabolomics

Lipidomics

Method development

Quantitative assays

Data analysis (R/Python)

Training users

Education

PhD or MS in Chemistry/Analytical Chemistry

Bachelor’s degree in Chemistry or related field

Tools

Analyst

MassLynx

Xcalibur

Sciex OS

Job description

The Yale University Chemical Metabolism Core in New Haven seeks an experienced analytical chemist/mass spectrometrist to develop and validate LC‑MS/MS assays, perform stable isotope tracing, and support metabolomics, lipidomics, and targeted quantitation across diverse research projects.

The role is bench‑based in a shared core facility, with responsibilities including method development, data processing, QC, and training users, while maintaining detailed records for reproducibility.