Senior Director of Biostatistics — Oncology Trials

Tango Therapeutics; Boston (MA); Presencial; USD 191.000 - 287.000; Jornada completa

Descripción de la vacante

Tango Therapeutics in Boston, MA, is seeking a Biostatistics expert reporting to the Senior Director, Biometrics. You will work with cross‑functional clinical teams responsible for statistical activities across Tango’s programs, including CROs.

The role involves leading trial design and analysis, contributing to protocols and regulatory submissions, and ensuring high‑quality data and documentation. A PhD or MS with relevant experience is required, with 10+ years in pharma/biotech and oncology

Formación

• PhD in statistics or related discipline or MS with directly relevant experience.
• At least 10 years’ experience in pharma/biotech.
• Oncology experience required.
• Design, analysis and reporting of clinical trials.
• Experience in regulatory submissions (INDs, NDAs, MAAs).
• Proficiency in SAS and R.
• Knowledge of SDTM and ADaM data standards.
• Experience with CROs and outsourced statistical services.
• Excellent written and oral communication skills.

Responsabilidades

• Serve as a biostatistics expert for Tango’s clinical programs.
• Provide strategic input to optimize trial designs in early and late phases.
• Coordinate statistical deliverables with internal teams and CROs.
• Develop statistical analysis plans and review SAPs.
• Oversee tables, figures, listings and data validation.
• Review eCRF designs to meet analysis needs.
• Contribute to regulatory submissions and clinical study reports.
• Lead process improvements for the Biostatistics function.

Conocimientos

Biostatistics leadership

SAS

R

Clinical trials design

Regulatory submissions

IND/ NDA / MAA experience

Communication skills

SDTM & ADaM

Educación

PhD in statistics or related discipline

MS with relevant experience

Descripción del empleo

Tango Therapeutics in Boston, MA, is seeking a Biostatistics expert reporting to the Senior Director, Biometrics. You will work with cross‑functional clinical teams responsible for statistical activities across Tango’s programs, including CROs.

The role involves leading trial design and analysis, contributing to protocols and regulatory submissions, and ensuring high‑quality data and documentation. A PhD or MS with relevant experience is required, with 10+ years in pharma/biotech and oncology