Director, Clinical Sciences — Oncology Trials Leader

Tango Therapeutics, Inc; Boston (MA); On-site; USD 190,000 - 286,000; Full time

Job summary

Tango Therapeutics, Inc is seeking a Director, Clinical Sciences to lead scientific contributions across clinical programs and to drive robust study design, execution, and interpretation of oncology trials.

You will collaborate with Clinical Development, Biostatistics, Regulatory Affairs and Medical Writing to ensure high-quality clinical program outcomes and regulatory readiness. This hands-on role requires significant prior leadership in clinical science and oncology settings.

Qualifications

• MD/PhD/PharmD/MS in a relevant scientific discipline.
• 10+ years of experience in clinical science or research.
• At least 5 years of experience in oncology.
• Strong analytical skills with statistical analysis and interpretation of clinical data.
• Excellent written and oral communication skills, with the ability to convey complex scientific concepts to diverse audiences.
• Experience working in a fast-paced environment.

Responsibilities

• Scientific contribution to one or more clinical programs to ensure the design, execution, and interpretation of clinical studies.
• Provide scientific leadership throughout design, execution, analysis, and interpretation of early- and late-stage oncology clinical trials.
• Partner with Clinical Development physicians, Clinical Operations, Biostatistics, Clinical Pharmacology, Pharmacovigilance, Regulatory Affairs, Translational Medicine, and Medical Writing to ensure high-quality execution of clinical programs.
• Contribute to development and review of key clinical documents, including protocols, investigator brochures, informed consent forms, clinical study reports, clinical development plans, and regulatory briefing materials.
• Interpret emerging clinical, safety, PK/PD, and biomarker data to inform study conduct, dose selection, expansion opportunities, and overall development strategy.
• Contribute scientific expertise to regulatory submissions and health authority interactions.
• Foster a collaborative, accountable, and scientifically rigorous culture within the Clinical Science function.
• Perform additional duties and responsibilities as required.

Skills

Clinical science experience

Oncology experience

Statistical analysis

Communication skills

Fast-paced environment

Education

MD/PhD/PharmD/MS in a relevant scientific discipline

Job description

Tango Therapeutics, Inc is seeking a Director, Clinical Sciences to lead scientific contributions across clinical programs and to drive robust study design, execution, and interpretation of oncology trials.

You will collaborate with Clinical Development, Biostatistics, Regulatory Affairs and Medical Writing to ensure high-quality clinical program outcomes and regulatory readiness. This hands-on role requires significant prior leadership in clinical science and oncology settings.