Senior Director, LNP Formulation & Process Innovation

miraibio; Cambridge (MA); On-site; USD 210,000 - 270,000; Full time

Job summary

Mirai Bio in Cambridge, MA seeks a Senior Director of Lipid Nanoparticle (LNP) Formulation & Process Development to lead the LNP formulation, process development, and small-scale production. You will guide scientific and operational strategy across programs, develop scalable capabilities, and mentor a growing team of scientists while partnering with clients.

The role requires deep LNP expertise, strong leadership, and client-facing skills to drive program success and transfer knowledge to

Qualifications

• Ph.D. in Pharmaceutical Sciences, Chemical Engineering, Bioengineering, Chemistry, Biochemistry, or related field with 12+ years of industry experience; M.S. with 14+ years; or B.S. with 16+ years.
• Extensive hands-on experience in LNP formulation and process development.
• Deep understanding of LNP composition, formation, purification, characterization, and relationships between process parameters and product attributes.
• Demonstrated ability to lead complex technical programs, interpret data, troubleshoot problems, and establish development strategies.

Responsibilities

• Lead the LNP formulation, process development, and small-scale production function supporting partner and internal programs.
• Establish technical strategy and best practices for LNP formulation, process development, characterization, and production across multiple payloads and applications.
• Provide senior technical leadership across multiple programs, including development strategy, experimental planning, data review, risk mitigation, and technical recommendations.
• Serve as a senior technical interface with clients and partners and support proposals, project scopes, presentations, and business development activities.
• Oversee non-GMP production of LNP formulations for in vitro, in vivo, and preclinical studies.
• Drive technical troubleshooting, process optimization, technology transfer, and continuous improvement of LNP production for mRNA, siRNA, gene-editing components, and other nucleic acid payloads.
• Establish workflows, documentation, and operational practices that improve quality, reproducibility, efficiency, and scalability.
• Lead, mentor, and develop the LNP team while managing priorities, resources, capacity, and organizational growth.
• Collaborate cross-functionally to align LNP development and production with broader program and company objectives.

Skills

LNP formulation

Process development

Team leadership

Client-facing

Education

PhD in Pharmaceutical Sciences or related

Job description

Mirai Bio in Cambridge, MA seeks a Senior Director of Lipid Nanoparticle (LNP) Formulation & Process Development to lead the LNP formulation, process development, and small-scale production. You will guide scientific and operational strategy across programs, develop scalable capabilities, and mentor a growing team of scientists while partnering with clients.

The role requires deep LNP expertise, strong leadership, and client-facing skills to drive program success and transfer knowledge to