Senior Director, Clinical Development – Nephrology

Travere Therapeutics; Columbia (SC); On-site; USD 246,000 - 332,000; Full time

Benefits offered by this job

Health insurance

Retirement plan

Job summary

Travere Therapeutics in San Diego, CA, seeks an Executive Director, Clinical Development to lead nephrology programs in rare kidney diseases. You will partner with Research, Regulatory, Biometrics, Clinical Operations, Medical Affairs, and Commercial to shape development strategy and drive program execution.

You will oversee multi-phase studies, provide leadership on trial design, analysis, and regulatory interactions, and contribute to portfolio governance in a globally oriented, mission-driven

Qualifications

• 10+ years of relevant experience in clinical research or drug development.
• Leadership role responsible for clinical development strategy and major program decisions.
• Experience leading clinical programs in nephrology, rare disease, or closely related areas.
• Strong understanding of trial design, dose selection, safety assessment, endpoints, and complex data interpretation.
• Experience with regulatory submissions and health authority interactions.

Responsibilities

• Lead the overall clinical development strategy for assigned trials, contributing to indication strategy, target product profile, clinical positioning, and lifecycle planning.
• Design and oversee clinical studies across phases, including protocol concept, eligibility criteria, endpoints, dose selection, and statistical considerations.
• Provide leadership for study conduct, protocol deviation review, and data interpretation.
• Lead analysis and interpretation of clinical data and author/review key documents (protocols, IBs, CSRs, abstracts, manuscripts, regulatory materials).
• Partner with Biometrics to define analysis strategy and ensure meaningful interpretation of efficacy, safety, PK/PD, and biomarkers.

Skills

Executive leadership

Clinical development

Regulatory strategy

Nephrology knowledge

Cross-functional leadership

Data interpretation

Education

MD/DO or equivalent medical degree

Nephrology specialization/training

Job description

Travere Therapeutics in San Diego, CA, seeks an Executive Director, Clinical Development to lead nephrology programs in rare kidney diseases. You will partner with Research, Regulatory, Biometrics, Clinical Operations, Medical Affairs, and Commercial to shape development strategy and drive program execution.

You will oversee multi-phase studies, provide leadership on trial design, analysis, and regulatory interactions, and contribute to portfolio governance in a globally oriented, mission-driven