Senior Director, Cardiometabolic MIDD & Clinical Pharmacology

GlaxoSmithKline plc; Waltham (MA); Hybrid; USD 223,000 - 371,000; Full time

Benefits offered by this job

Health insurance

Retirement benefits

Paid holidays

Vacation

Parental leave

Medical leave

Job summary

GlaxoSmithKline plc is seeking a Senior Director to lead Clinical Pharmacology Modeling and Simulation across RIIRU programs. You will shape MIDD strategies, coordinate CPMS activities across assets, and drive regulatory-ready pharmacology content for RIIRU portfolios.

The role interfaces with biology, data science, translational imaging, and AI/ML teams, enabling cross-functional decision support and accelerated drug development in respiratory and metabolic diseases.

Qualifications

• PhD, MD, or PharmD required in pharma/biotech with deep clinical pharmacology knowledge.
• 8+ years of industry experience in clinical pharmacology, modelling/simulation and drug development.
• Experience in pharmacometrics and cross-functional collaboration with senior stakeholders.
• Experience in Cardiovascular and Metabolic Diseases therapy areas.

Responsibilities

• Design and execute Model Informed and Clinical Pharmacology strategies across RIIRU.
• Coordinate CPMS activities and align global CPMS/CPQM priorities with leadership.
• Draft regulatory content and ensure regulatory readiness for RIIRU projects.
• Build cross-functional partnerships to embed quantitative approaches in decision making.

Skills

Drug Design

Drug Development

Drug Discovery

Molecular Modeling

Pharmacodynamics

Pharmacokinetics

Pharmacology

Pharmacometrics

Pharmacovigilance

Study Design

Regulatory Compliance

Regulatory Affairs

Clinical Pharmacology

Education

PhD, MD, or PharmD

Tools

Modeling & Simulation

Job description

GlaxoSmithKline plc is seeking a Senior Director to lead Clinical Pharmacology Modeling and Simulation across RIIRU programs. You will shape MIDD strategies, coordinate CPMS activities across assets, and drive regulatory-ready pharmacology content for RIIRU portfolios.

The role interfaces with biology, data science, translational imaging, and AI/ML teams, enabling cross-functional decision support and accelerated drug development in respiratory and metabolic diseases.