Director of Cardiovascular & Metabolic MIDD Strategy

GlaxoSmithKline; Waltham (MA); Hybrid; USD 223,000 - 371,000; Full time

Benefits offered by this job

Health care

Retirement benefits

Paid holidays

Vacation

Caregiver/Parental leave

Medical leave

Job summary

GlaxoSmithKline is seeking a Senior Director of Cardiovascular and Metabolic Diseases within Clinical Pharmacology Modeling and Simulation. The role will influence MIDD strategy across the drug development lifecycle and report to RIIRU leadership.

The position involves collaboration with CPQM teams and cross-functional partners to shape portfolio strategy and regulatory support. Based in the US with hybrid work options, the role requires extensive leadership experience in pharmacometrics, drug

Qualifications

• PhD, MD, or PharmD degree required.
• 8+ years of industry experience in clinical pharmacology, modelling/simulation and drug development.
• Experience in pharmacometrics applied to clinical questions.
• Experience working with senior stakeholders in cross functional environment.
• Experience in Cardiovascular and Metabolic Diseases therapy areas.

Responsibilities

• Design and execute Model Informed and Clinical Pharmacology strategies to de-risk and accelerate RIIRU programs.
• Coordinate CPMS activities across RIIRU assets and align global CPMS/CPQM priorities.
• Ensure regulatory-ready evidence and robust study designs across RIIRU portfolio.
• Build cross-functional partnerships with CPQM, biology, data science, and regulatory teams.
• Lead external engagement and scientific leadership through publications and conferences.

Skills

Drug Design

Drug Development

Drug Discovery

Pharmacology

Pharmacometrics

Regulatory Compliance

Pharmacovigilance

Pharmacokinetics

Pharmacodynamics

Molecular Modeling

Study Design

Target Validation

Education

PhD/MD/PharmD

Job description

GlaxoSmithKline is seeking a Senior Director of Cardiovascular and Metabolic Diseases within Clinical Pharmacology Modeling and Simulation. The role will influence MIDD strategy across the drug development lifecycle and report to RIIRU leadership.

The position involves collaboration with CPQM teams and cross-functional partners to shape portfolio strategy and regulatory support. Based in the US with hybrid work options, the role requires extensive leadership experience in pharmacometrics, drug