Senior Director, Cardiovascular & Metabolic MIDD Strategy

GlaxoSmithKline; Philadelphia (Philadelphia County); Hybrid; USD 223,000 - 371,000; Full time

Benefits offered by this job

Annual bonus

Long-term incentive

Health benefits

Retirement benefits

Paid holidays

Parental leave

Job summary

GlaxoSmithKline seeks a Senior Director to lead Cardiovascular and Metabolic Disease Clinical Pharmacology Modeling and Simulation. The role guides end-to-end MIDD across drug development, from first-in-human studies to filing and lifecycle management, reporting to RIIRU.

The position emphasizes regulatory strategy, data-driven decision making and leadership of a high-impact team. The role sits within CPQM and collaborates with digital medicine, translational imaging, biology, data science and

Qualifications

• PhD, MD or PharmD required.
• 8+ years in clinical pharmacology, modelling/simulation and drug development.
• Experience with pharmacometrics applied to clinical questions.
• Experience working with senior stakeholders in cross-functional teams.
• Experience in Cardiovascular and Metabolic Diseases.

Responsibilities

• Design and execute MIDD and ClinPharm strategies to de-risk RIIRU programs.
• Coordinate CPMS activities across RIIRU assets with global priorities.
• Draft and review clinical pharmacology regulatory content for approvals.
• Build cross-functional partnerships with CPQM and related functions.
• Engage externally to raise GSK's profile in MIDD and AI/ML integration.

Skills

Clinical Pharmacology

Modeling & Simulation

Pharmacometrics

Regulatory Strategy

MIDD

QSP

Cross-functional leadership

Education

PhD, MD, or PharmD

Job description

GlaxoSmithKline seeks a Senior Director to lead Cardiovascular and Metabolic Disease Clinical Pharmacology Modeling and Simulation. The role guides end-to-end MIDD across drug development, from first-in-human studies to filing and lifecycle management, reporting to RIIRU.

The position emphasizes regulatory strategy, data-driven decision making and leadership of a high-impact team. The role sits within CPQM and collaborates with digital medicine, translational imaging, biology, data science and