Senior Director, AI Commercial Architecture

Vertex Pharmaceuticals LLC; Boston (MA); Hybrid; USD 307,800 - 376,200; Full time

Job summary

Vertex Pharmaceuticals LLC is seeking a Senior Director to lead commercialization technology architecture. You will define target architectures, govern integration patterns, and establish platform standards for scalable, secure AI-enabled commercial systems.

You will partner with Product, Data, and Engineering teams to ensure production-ready designs and regulatory compliance across CRM and enterprise platforms in a hybrid/on-site capacity.

Qualifications

• Experience defining target-state architectures across commercial/medical ecosystems.
• Proven ability to design scalable integrations and data architectures.
• Hands-on knowledge of cloud/data warehouses and modern data stacks.
• Experience with AI/ML and regulated environments (SOX, GxP) is preferred.

Responsibilities

• Define and govern target-state architecture and engineering standards for AI-enabled systems.
• Lead integration patterns across Salesforce, Veeva, and downstream data platforms.
• Establish environment, deployment, and DevOps patterns within Commercial/Medical domains.
• Ensure architecture aligns with SOX, privacy, and security requirements.

Skills

Enterprise architecture

Solution design

Distributed systems

CRM platforms

AI/ML architectures

Regulatory compliance

Stakeholder collaboration

Education

Bachelor’s or Master’s in CS/Engineering

Tools

Salesforce

Veeva

Snowflake

Databricks

AWS

Azure

Job description

Vertex Pharmaceuticals LLC is seeking a Senior Director to lead commercialization technology architecture. You will define target architectures, govern integration patterns, and establish platform standards for scalable, secure AI-enabled commercial systems.

You will partner with Product, Data, and Engineering teams to ensure production-ready designs and regulatory compliance across CRM and enterprise platforms in a hybrid/on-site capacity.