Scientist III # 26-23218

US Tech Solutions; Worcester (MA); On-site; USD 84,000 - 88,000; Part time

Job summary

US Tech Solutions is seeking a Scientist to join the Analytical Development team in Worcester, MA, focusing on analytical characterization of biologics. The role involves LC-MS, HPLC, and biophysical analyses to support early to commercial programs.

You will develop and perform assays and contribute to method development and optimization. The position is a 12-month contract in Worcester, with compensation stated per hour and a focus on accuracy, reproducibility, and timely data reporting.

Qualifications

• BS or MS in chemistry/biochemistry/biology or related field.
• Hands-on proteomics/biomolecule characterization knowledge is a plus.
• Experience with LC-MS, HPLC, and biophysical analyses is desirable.

Responsibilities

• Perform mass spectrometry analyses (LC-MS) of biologics to verify sequence and PTMs.
• Execute separation methods (HPLC/AKTA) for variant analysis.
• Apply biophysical methods (DSC) to support characterization studies.
• Design and execute method development experiments and investigations.
• Support process development with material analysis and metabolomics workflows.
• Document experiments and results in electronic lab notebooks; draft reports.

Job description

$60.50-$63.75 per hour

Worcester, MA

Contract

Duration: 12 months contract

Job Description:

• Client’s Bioresearch Center in Worcester, MA. The team is responsible for the development, qualification, and execution of analytical methods to provide product and process understanding for biological entities from discovery through commercial stages.The Client is searching for a highly motivated Scientist to join their Analytical Development team at

• As a Scientist, you will be a part of the Analytical Characterization Group (ACG) within the Analytical Development Department. ACG focuses on providing routine, investigative, and in-depth characterization analyses of Client’s biologics to support product and process development for early-phase, late-phase, and commercial programs using liquid chromatography mass spectrometry (LC-MS), spectroscopy and various other biophysical assays.

• The successful candidate will contribute to the development and performance of analytical assays and will contribute to the continuous improvement and innovation within ACG and the Analytical Development Department.

Key Responsibilities:

• Perform mass spectrometry analyses (i.e., intact/reduced mass analysis by LC-MS and peptide mapping by LC-MS) of Client’s biologics to provide sequence verification and post-translational modification profiles.

• Independently perform separation methods (e.g., fractionation & analysis of variants) using HPLC and AKTA.

• Perform biophysical methods (e.g., DSC) of Client’s biologics to support characterization studies.

• Design and execute experiments for method development and/or investigations.

• Support process development by performing raw material analysis using vibrational spectroscopy and executing metabolomics experiments using mass spectrometry.

• Generate and communicate precise, reliable, and reproducible data in a timely manner.

• Organize and document experiments and results in an electronic laboratory notebook.

• Draft protocols, method development reports, and technical characterization reports.

• Maintain lab equipment.

Qualifications:

• Bachelors or Masters in chemistry, biology, biochemistry, or related technical discipline with typically 5+ (BS) or 2+ (MS) years of relevant experience in biotech/pharmaceutical industry setting.

• Hands‑on experience with protein mass spectrometry, liquid chromatography, capillary electrophoresis, and protein biophysical characterization.

• Knowledge of HPLC or AKTA instrumentation.

• Fundamental understanding of protein structure, post‑translational modifications, and analytical methods used for protein characterization.

• Working knowledge of bioinformatics tools to process and analyze mass spectrometry data is highly desirable.

• Knowledge of vibrational spectroscopy (e.g., IR, NIR and Raman) and multivariate analysis is desirable.

• Proficient with Windows 10 and Microsoft Office (Outlook, Excel, Word, and PowerPoint).

• Excellent written communication, oral communication, organization, and multitasking skills.

• Hardworking and motivated to drive both efficiency and quality.

• Understand and adhere to corporate standards regarding code of conduct, safety, and appropriate handling of materials.

2. Equal Employment Opportunity (EEO) Statement:

US Tech Solutions is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran.

3. AI Statement:

By applying, you acknowledge that AI‑assisted tools may be used during hiring.