Senior Scientist

Mindlance; Worcester (MA); On-site; USD 70,000 - 90,000; Full time

Job summary

Mindlance is seeking a motivated scientist to join the Biologics CMC Developability team based in Worcester, MA. This role involves characterizing biologic drug candidates and ensuring compliance with corporate documentation standards.

You will perform in-depth LC-MS and chromatography analyses, prepare scientific presentations, and maintain laboratory equipment. Ideal candidates have a BS or MS in a relevant field, significant lab experience, and strong collaboration skills.

Qualifications

• 5+ years (BS) or 2+ years (MS) of biopharmaceutical industry experience.
• Hands-on experience with protein mass-spectrometry.
• Experience with liquid chromatography methods.

Responsibilities

• Perform LC-MS based characterization of therapeutic biologic molecules.
• Conduct liquid chromatography-based characterization.
• Prepare and deliver scientific presentations of results.

Skills

Protein mass-spectrometry

Liquid chromatography

Independent thinking

Data analysis with MS Excel

Team collaboration

Education

BS or MS in Biochemistry, Biology, Chemistry, or equivalent

Ph.D. in biopharmaceutical sciences

Tools

Liquid handling robots

GraphPad

Job description

Contract

1 year - based on performance and business needs

Job Location

Worcester, MA

Job Description

The Biologics CMC Developability team is an integral part of the Biologics CMC Drug Product Development Org. The team is responsible for identifying biophysical- and chemical liabilities in discovery-stage biologic drug candidates to guide lead selection, and for characterizing the key CMC attributes important for biologic drug development. We have an exciting opportunity for a motivated scientist to join this team.

Key Responsibilities

• Perform in-depth LC-MS based characterization of therapeutic biologic molecules and their post‑translational modifications.
• Conduct liquid chromatography‑based characterization of biologic drug candidates (size exclusion, ion exchange, and reverse phase).
• Execute experimental protocols, collect results, and perform data analysis carefully and independently.
• Maintain excellent documentation of work including electronic lab notebook and protocols.
• Prepare and deliver concise scientific presentations of experimental results.
• Oversee maintenance of key laboratory equipment and routine laboratory operations.
• Build strong relationships with other team members and across groups.
• Understand and adhere to corporate standards regarding code of conduct, safety, and documentation compliance.

Qualifications

• BS or MS in Biochemistry, Biology, Chemistry (or equivalent, e.g., Chemical Engineering, Pharmaceutical Sciences) with 5+ years (BS) or 2+ years (MS), or Ph.D. with 0+ years of biopharmaceutical industry experience.
• Hands‑on experience with protein mass‑spectrometry (subunit analysis, peptide mapping, disulfide mapping) and data processing.
• Experience with liquid chromatography methods commonly used for characterization of biologic proteins.
• Experience with liquid handling robots and their programming would be highly beneficial.
• Demonstrated track record of independent thinking, creativity, and scientific accomplishment.
• Highly responsible and self‑motivated; skills to plan and conduct experiments with high quality and timely deliverables.
• Ability to perform data analysis using MS Excel & GraphPad.
• Team player with excellent collaboration and communication skills.

Mindlance is an Equal Opportunity Employer and does not discriminate in employment on the basis of – Minority/Gender/Disability/Religion/LGBTQI/Age/Veterans.