RNA Pilot Manufacturing Scientist - Fast-Track Dev

Bristol Myers Squibb; Cambridge (MA); On-site; USD 94,000 - 114,000; Full time

Job summary

Bristol Myers Squibb in Cambridge, MA seeks an Associate Scientist to support an RNA Pilot Manufacturing operation within a fast-paced, science-driven environment. You will partner with CMC functions to ensure timely material delivery, technical readiness, and operational excellence.

The role emphasizes phase-appropriate manufacturing, quality, compliance, and continuous improvement while enabling rapid execution across early and late-stage development.

Qualifications

• Degree in Bio/Chemical Engineering, Bio/Chemistry, or related field.
• BS with 2-4+ years’ experience in science related disciplines.
• MS with 1-2+ years’ experience in science related disciplines.
• Experience in process unit operations relevant to RNA manufacturing including bioreactors, chromatography, and filtration.
• Knowledge of technology transfer from PD to the pilot facility and from the pilot facility to GMP manufacturing.
• Strong track record of utilizing standardized operations, KPI management, and production documentation systems.
• Experience with compiling and interpreting RNA analytics and biophysical characterization techniques for RNA such as HPLC, CE, ELISAs, and cell-based assays.
• Prior management and mentorship experience; passion for people management and development
• Ability to work independently as well as part of a team in a highly dynamic, fast-paced, matrixed environment with rapidly evolving priorities.
• Demonstrated continuous improvement mindset, driving efficiencies, process improvements across diverse initiatives.

Responsibilities

• Support and execute RNA manufacturing operations supporting nonGMP manufacturing activities.
• Work in an agile development manufacturing model in the RNA space capable of rapidly delivering material for various program needs.
• Ensure manufacturing operations are executed in a phase-appropriate manner, balancing speed, compliance, scientific rigor, and operational discipline.
• Partner with analytical testing laboratories to ensure sample submission, investigation support, and timely release of material.
• Enable technical problem-solving during manufacturing campaigns, including real-time escalation, root-cause analysis, and implementation of corrective and preventive actions.
• Maintain systems for tracking process performance using ELN workflows and multivariate data analysis tools.
• Ensure learnings from manufacturing activities are captured, communicated, and incorporated into future strategies.

Skills

RNA analytics

Unit operations

KPI management

Documentation systems

Team leadership

Problem solving

Independent & team work

Bioreactors

Chromatography

Filtration

Continuous improvement

Education

BS in Bio/Chemical Engineering or related field

MS in related field

Tools

ELN

Multivariate data analysis tools

Job description

Bristol Myers Squibb in Cambridge, MA seeks an Associate Scientist to support an RNA Pilot Manufacturing operation within a fast-paced, science-driven environment. You will partner with CMC functions to ensure timely material delivery, technical readiness, and operational excellence.

The role emphasizes phase-appropriate manufacturing, quality, compliance, and continuous improvement while enabling rapid execution across early and late-stage development.