Principal Scientist, Bioanalytical PK for Biologics

HireLifeScience; Boston (MA); On-site; USD 176,000 - 277,000; Full time

Job summary

HireLifeScience in Boston seeks a Principal Scientist to lead bioanalytical strategies for biologics in drug discovery. You will oversee ligand binding assays and mass spectrometry, interact with discovery teams, and shape PK/PD interpretations across immunology and oncology portfolios.

The role requires Ph.D. or equivalent with 6+ years, or a Master’s with 10+ years, and offers visibility to senior leadership in a fast-paced, science-driven environment. Domestic relocation may be considered.

Qualifications

• Ph.D. (with 6+ years relevant experience) or Master's (minimum 10 years relevant experience) in biochemistry, chemistry, pharmacology, pharmaceutical sciences, biomedical engineering or related field.
• Relevant experience showing increasing responsibility in an industrial/academic setting.

Responsibilities

• Lead bioanalytical strategies for biologics, including method development and data interpretation.
• Manage a team of PDMB scientists developing ligand binding assays and MS-based strategies.
• Represent DMPK activities on cross-functional discovery teams and global strategy contributions.

Skills

ADME

Bioanalysis

PKPD Modeling

Pharmacokinetics

Pharmacology

Cross-Functional Teamwork

Team Leadership

Drug Development

Education

Ph.D

Master's

Tools

Phoenix WinNonlin

Berkeley Madonna

MATLAB

Job description

HireLifeScience in Boston seeks a Principal Scientist to lead bioanalytical strategies for biologics in drug discovery. You will oversee ligand binding assays and mass spectrometry, interact with discovery teams, and shape PK/PD interpretations across immunology and oncology portfolios.

The role requires Ph.D. or equivalent with 6+ years, or a Master’s with 10+ years, and offers visibility to senior leadership in a fast-paced, science-driven environment. Domestic relocation may be considered.