Principal Scientist, Biologics PK & Bioanalysis

MSD Malaysia; Boston (MA); Hybrid; USD 176,000 - 277,000; Full time

Job summary

Merck & Co., Inc. Boston invites applications for Principal Scientist, Pharmacokinetics, Biologics within the PDMB group.

The role leads bioanalytical strategy for biologics, guides ligand binding assays and MS methods, and represents DMPK on cross-functional discovery teams. The successful candidate will manage a team of PDMB scientists, drive data interpretation of PK/PD and translate findings into project decisions across oncology and immunology programs, with potential contributions to other

Qualifications

• Ph.D. with 6+ years of relevant experience or Master’s with 10+ years of relevant experience.
• Record of increasing responsibility and independence in industrial/academic settings.

Responsibilities

• Lead bioanalytical strategies for biologics including ligand binding assays and MS-based approaches.
• Manage a team of lab-based PDMB scientists developing assays and MS methods.
• Serve as project-team SME on multiple modality DMPK activities in oncology and immunology.
• Collaborate globally to shape translational PK/PD strategies across discovery and early development.

Skills

ADME

Bioanalysis

Bioanalytical Method Development

Biologics

Cross-Functional Teamwork

Drug Development

Drug Discovery Research

Drug Metabolism

Ligand Binding

Pharmaceutical Sciences

Pharmaceutics

Pharmacodynamics

Pharmacokinetics

Pharmacology

PKPD Modeling

Therapeutic Proteins

Education

Ph.D (6+ years experience)

Master’s (10+ years experience)

Tools

Phoenix WinNonlin

Berkeley Madonna

MATLAB

Job description

Merck & Co., Inc. Boston invites applications for Principal Scientist, Pharmacokinetics, Biologics within the PDMB group.

The role leads bioanalytical strategy for biologics, guides ligand binding assays and MS methods, and represents DMPK on cross-functional discovery teams. The successful candidate will manage a team of PDMB scientists, drive data interpretation of PK/PD and translate findings into project decisions across oncology and immunology programs, with potential contributions to other