Peptide Upstream Scientist, Mixed Modality Manufacturing

Initial Therapeutics, Inc.; Lebanon (IN); On-site; USD 66,000 - 172,000; Full time

Job summary

Lilly is seeking a Mixed Modality (Peptide Upstream) Scientist for the Lilly Medicine Foundry in Lebanon, IN. This role focuses on transferring peptide upstream manufacturing processes from development to pilot plant operations, enabling early‑phase cGMP production in grams to kilograms scale.

The position requires a BS or MS in chemistry and 3+ years in peptide chemistry, with experience in SPPS, peptide purification, and analytical methods.

Qualifications

• BS or MS in chemistry or related field.
• 3+ years of peptide chemistry experience or manufacturing environments.
• Authorized to work in the United States on a full‑time basis.

Responsibilities

• Perform peptide upstream synthesis and assess routes for transfer to pilot plant operations.
• Coordinate with safety, process engineering and analytical teams.
• Document batch records, tech transfer plans and SOPs for plant readiness.
• Assist in scale‑up and qualification of processes from development to cGMP readiness.
• Maintain organized lab notebooks and ensure data traceability for transfers.

Skills

Peptide chemistry

SPPS

Analytical methods

Education

B.S. in Chemistry

M.S. in Chemistry

Tools

HPLC/UPLC

LC-MS

NMR

Job description

Lilly is seeking a Mixed Modality (Peptide Upstream) Scientist for the Lilly Medicine Foundry in Lebanon, IN. This role focuses on transferring peptide upstream manufacturing processes from development to pilot plant operations, enabling early‑phase cGMP production in grams to kilograms scale.

The position requires a BS or MS in chemistry and 3+ years in peptide chemistry, with experience in SPPS, peptide purification, and analytical methods.