Peptide Downstream Scientist - Process Transfer

Biopharma Careers

Lebanon (KY)

On-site

USD 66,000 - 172,000

Full time

14 days+

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Benefits offered by this job

Company 401(k)
Pension
Vacation benefits
Medical coverage
Dental coverage
Vision coverage
Flexible benefits

Job summary

Lilly is seeking a passionate Mixed Modality (Peptide Downstream) Scientist to help transfer peptide downstream processes from development to pilot plant operations, enabling early-phase cGMP manufacturing for grams to kilogram scale. You will evaluate purification strategies and ensure plant readiness with RP chromatography, TFF, and lyophilization.

Candidates should have 3+ years in peptide purification/manufacturing, strong analytical skills in HPLC/UPLC, LC-MS, and NMR, and eligibility to

Qualifications

  • BS/MS in chemistry, chemical engineering, or related field.
  • 3+ years of experience in peptide purification and/or manufacturing.
  • Authorized to work in the United States full-time; no visa sponsorship provided.

Responsibilities

  • Evaluate and facilitate transfer of peptide downstream processes from development to pilot plant operations.
  • Perform peptide purification and isolation; assess purification methods.
  • Operate and troubleshoot peptide downstream equipment (e.g., TFF, RP chromatography, lyophilization).
  • Document procedures, batch records, and technical transfers; support CAPAs and deviations.

Skills

Peptide downstream chemistry
Purification methods
HPLC/UPLC
TFF

Education

B.S. or M.S. in chemistry or related

Tools

HPLC/UPLC
LC-MS
NMR

Job description

Lilly is seeking a passionate Mixed Modality (Peptide Downstream) Scientist to help transfer peptide downstream processes from development to pilot plant operations, enabling early-phase cGMP manufacturing for grams to kilogram scale. You will evaluate purification strategies and ensure plant readiness with RP chromatography, TFF, and lyophilization.

Candidates should have 3+ years in peptide purification/manufacturing, strong analytical skills in HPLC/UPLC, LC-MS, and NMR, and eligibility to

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