Peptide Upstream Process Transfer Lead

BioSpace; Lebanon (IN); Presencial; USD 131.000 - 211.000; Jornada completa

Descripción de la vacante

Lilly is seeking a passionate chemist to join the PTE team in Lebanon, Indiana, advancing the Lilly Medicine Foundry’s peptide upstream programs. You will transfer gram-to-kilogram scale peptide processes to pilot and early-phase cGMP manufacturing, ensuring plant readiness and robust documentation.

Ideal candidates bring strong peptide chemistry expertise, SPPS proficiency, and proven ability to lead cross-functional tech transfers, scale-up, and data-driven problem solving in a manufacturing

Formación

• B.S., M.S., or Ph.D. in chemistry, chemical engineering, or related field.
• B.S. with 8+ years, M.S. with 5+ years, or Ph.D. with 2+ years in peptide chemistry/manufacturing.

Responsabilidades

• Translate and transfer peptide upstream processes from development to manufacturing with supervision.
• Oversee transfer of peptide processes; ensure scalability and plant fit; troubleshoot issues.
• Assess peptide synthesis routes and evaluate safety with process engineering.
• Perform SPPS and cleavage/ precipitation; document lab trials for plant readiness.
• Lead process documentation: transfer plans, SOPs, batch records, deviation reports.
• Drive continuous improvement, CAPAs, RCA, and cross-functional collaboration.

Conocimientos

Peptide chemistry

Process transfer

SPPS

Scale-up experiments

Root cause analysis

Cross-functional collaboration

Technical reporting

Educación

Ph.D. in chemistry or related field

M.S. in chemistry

B.S. in chemistry

Herramientas

HPLC/UPLC

LC-MS

GC

NMR

TFF

Lyophilization

Descripción del empleo

Lilly is seeking a passionate chemist to join the PTE team in Lebanon, Indiana, advancing the Lilly Medicine Foundry’s peptide upstream programs. You will transfer gram-to-kilogram scale peptide processes to pilot and early-phase cGMP manufacturing, ensuring plant readiness and robust documentation.

Ideal candidates bring strong peptide chemistry expertise, SPPS proficiency, and proven ability to lead cross-functional tech transfers, scale-up, and data-driven problem solving in a manufacturing