Peptide Process Translation Lead — Foundry Startup

Eli Lilly and Company; Lebanon (IN); Presencial; USD 131.000 - 211.000; Jornada completa

Ventajas ofrecidas por este puesto de trabajo

401(k) matching

Pension plan

Vacation benefits

Medical, dental, vision benefits

Flexible benefits

Life insurance

Time off and leave benefits

Well-being programs

Descripción de la vacante

Lilly Medicine Foundry in Lebanon, Indiana, and the Lilly Technology Center in Indianapolis seek experienced chemists to lead peptide upstream process transfer from development to manufacturing, ensuring scalable, compliant cGMP operations for clinical supply.

The role emphasizes SPPS, cleavage and precipitation, process optimization, and collaboration across safety, QA, and manufacturing teams to drive rapid, reliable plant readiness and continuous improvement.

Formación

• Ph.D./M.S./B.S. with relevant peptide chemistry/manufacturing experience.
• Experience in peptide upstream processes and scale-up.
• Solid phase peptide synthesis (SPPS) and cleavage/deprotection knowledge.

Responsabilidades

• Lead transfer of peptide upstream processes to manufacturing.
• Ensure plant readiness and process fit for kilo-scale production.
• Conduct root cause analysis and troubleshooting of peptide processes.
• Collaborate with safety, process engineering, and analytical groups.
• Prepare batch records, tech transfer plans, SOPs and deviation reports.

Conocimientos

Peptide chemistry

SPPS

Scale-up

Cross-functional collaboration

Analytical techniques

Root cause analysis

Educación

Ph.D. in chemistry or related field

M.S. in chemistry or related field

B.S. in chemistry or related field

Herramientas

HPLC/UPLC

LC-MS

GC

NMR

Descripción del empleo

Lilly Medicine Foundry in Lebanon, Indiana, and the Lilly Technology Center in Indianapolis seek experienced chemists to lead peptide upstream process transfer from development to manufacturing, ensuring scalable, compliant cGMP operations for clinical supply.

The role emphasizes SPPS, cleavage and precipitation, process optimization, and collaboration across safety, QA, and manufacturing teams to drive rapid, reliable plant readiness and continuous improvement.