Oligonucleotide Process Transfer Lead

BioSpace; Lebanon (IN); On-site; USD 131,000 - 211,000; Full time

Job summary

Lilly is seeking a passionate scientist to join the Process Translation and Execution team at the Lilly Medicine Foundry in Lebanon, Indiana. You will drive transfer of oligonucleotide processes from development to pilot plant operations, with emphasis on scale-up and robust documentation.

The role demands strong data analysis, cross-functional collaboration, and leadership to ensure readiness across synthesis, purification, and analytical steps.

Qualifications

• PhD/MS/BS in a relevant field with chemistry/biochemical focus.
• Experience in oligonucleotide product/process development or related roles.
• Strong data analysis and problem-solving capabilities.
• Ability to lead cross-functional technical projects.

Responsibilities

• Lead oligonucleotide process transfers from development to pilot plant operations.
• Define scale-up approaches for synthesis and purification methods.
• Serve as technical authority on oligonucleotide unit operations and documentation.
• Mentor scientists and collaborate with CMC, Product R&D, and Manufacturing.

Skills

Oligonucleotide process knowledge

Data analysis

Cross-functional collaboration

Technical leadership

HPLC/UPLC

LC-MS

GC

Education

B.S., M.S., or Ph.D in Chemistry, Biochemistry, Chemical/Biochemical Engineering, or related discipline

Tools

HPLC/UPLC

LC-MS

GC

Job description

Lilly is seeking a passionate scientist to join the Process Translation and Execution team at the Lilly Medicine Foundry in Lebanon, Indiana. You will drive transfer of oligonucleotide processes from development to pilot plant operations, with emphasis on scale-up and robust documentation.

The role demands strong data analysis, cross-functional collaboration, and leadership to ensure readiness across synthesis, purification, and analytical steps.