Peptide Upstream Scientist - Mixed Modality, Foundry

BioSpace; Lebanon (IN); On-site; USD 66,000 - 172,000; Full time

Benefits offered by this job

Company bonus

401(k) plan

Healthcare benefits

Job summary

Lilly Technology Center and Lilly Medicines Foundry in Lebanon, Indiana, are seeking passionate chemists to join the PTE team. The role focuses on translating peptide upstream processes from development to pilot plant operations, enabling cGMP manufacturing for clinical supply.

Initial location at Indianapolis/Carmel with permanent site in Lebanon; travel is limited. You will collaborate across disciplines to drive readiness, implement process improvements, and deliver robust technical

Qualifications

• B.S. or M.S. in chemistry, chemical engineering, or related field.
• 3+ years of experience in peptide chemistry and/or manufacturing environments involving synthetic peptide API or drug substance.
• Authorized to work in the United States on a full‑time basis; no sponsorship provided.

Responsibilities

• Perform synthetic peptide chemistry and evaluate routes from early phase labs to pilot plant operations.
• Familiarity with SPPS, Cleavage & Precipitation, and ensuring plant readiness.
• Document tech transfer plans, SOPs, batch records, and deviation reports.
• Support process troubleshooting, RCA, and CAPAs with cross‑functional teams.
• Maintain detailed lab notebooks with analytical data for technical packages.

Skills

Peptide chemistry

SPPS

Scale-up

Analytical methods

Documentation

Education

B.S. in chemistry

M.S. in chemistry

Tools

HPLC/UPLC

LC-MS

NMR

Job description

Lilly Technology Center and Lilly Medicines Foundry in Lebanon, Indiana, are seeking passionate chemists to join the PTE team. The role focuses on translating peptide upstream processes from development to pilot plant operations, enabling cGMP manufacturing for clinical supply.

Initial location at Indianapolis/Carmel with permanent site in Lebanon; travel is limited. You will collaborate across disciplines to drive readiness, implement process improvements, and deliver robust technical