LNP Analytics Scientist I

Stylus Medicine; Cambridge (MA); Presencial; USD 105.000 - 115.000; Jornada completa

Descripción de la vacante

Stylus Medicine in Cambridge, MA is seeking an Associate Scientist to join the analytical development team and advance LNP characterization for in vivo delivery of genome engineering materials. You will support delivery projects and help develop novel analytical methods.

You will work with cross-functional teams to assess biodistribution, safety and efficacy of LNP formulations, author SOPs, study plans and reports, and stay abreast of advancing LNP technologies.

Formación

• Undergraduate or master’s degree in biochemistry, chemical engineering, materials science, or a related field
• 2-4 years of industry/academic experience focusing on LNP characterization
• Prior experience with characterization of targeted nanoparticles is strongly preferred
• Strong foundation in lipid chemistry, formulation development, and analytical techniques
• Familiarity with gene editing modalities or nucleic acid delivery (e.g. CRISPR/Cas, base editing, mRNA, DNA) is a plus
• Demonstrated ability to thrive in a fast-paced, innovative environment
• Strong communication skills, with the ability to collaborate effectively with cross-functional teams to meet project deliverables and timelines
• Demonstrated ability to work independently, multitask effectively, and maintain strong written documentation

Responsabilidades

• Leverage expertise in lipid chemistry, LNP formulation and analytical characterization to advance novel gene editing modalities across different stages of drug development
• Develop methods such as BLA, CBQCA, DLS, , UPLC, HPLC-CAD, IP‑RP HPLC, LC‑MS/MS, CGE, BLI/SPR, ELISA and ddPCR/qPCR to screen and support optimal LNP formulations for in vitro and in vivo applications
• Author standard operating procedures, study plans, reports, and present findings to project teams and leadership
• Work in close collaboration with the cross-functional teams to support in vitro and in vivo experiments assessing biodistribution, safety and efficacy of LNP formulations
• Foster external collaborations and stay abreast of emerging trends and innovations in LNP technology, proposing new approaches to enhance the company’s delivery platforms, as appropriate

Conocimientos

Lipid chemistry

Formulation development

Analytical techniques

Written documentation

Cross-functional collaboration

Educación

Bachelor's or Master's in Biochemistry / related field

Herramientas

BLA

CBQCA

DLS

UPLC / HPLC

LC–MS/MS

ELISA / ddPCR/qPCR

Descripción del empleo

Stylus Medicine in Cambridge, MA is seeking an Associate Scientist to join the analytical development team and advance LNP characterization for in vivo delivery of genome engineering materials. You will support delivery projects and help develop novel analytical methods.

You will work with cross-functional teams to assess biodistribution, safety and efficacy of LNP formulations, author SOPs, study plans and reports, and stay abreast of advancing LNP technologies.