LNP Analytics Scientist – Gene Delivery & Method Development

Stylus Medicine, Inc.; Cambridge (MA); Presencial; USD 90.000 - 130.000; Jornada completa

Descripción de la vacante

Stylus Medicine, Inc. is seeking an Associate Scientist to join our analytical development team, focusing on LNP characterization for in vivo genome delivery.

You will drive development of analytical techniques and provide support to the delivery team, reporting to the Principal Scientist, LNP Analytics. You will collaborate with cross-functional teams on in vitro and in vivo studies, contribute to SOPs and study plans, and help advance transformative in vivo genetic medicines from discovery

Formación

• Undergraduate or master's degree in biochemistry, chemical engineering, materials science, or a related field.
• 2–4 years of industry/academic experience focusing on LNP characterization.
• Prior experience with characterization of targeted nanoparticles is strongly preferred.
• Strong foundation in lipid chemistry, formulation development, and analytical techniques.
• Familiarity with gene editing modalities or nucleic acid delivery (e.g. CRISPR/Cas, base editing, mRNA, DNA) is a plus.
• Demonstrated ability to thrive in a fast-paced, innovative environment.
• Strong communication skills, with the ability to collaborate effectively with cross-functional teams to meet project deliverables and timelines.

Responsabilidades

• Leverage lipid chemistry, LNP formulation and analytics to advance gene editing modalities.
• Develop methods such as BLA, CBQCA, DLS, UPLC, HPLC-CAD, LC-MS/MS, ELISA and ddPCR/qPCR.
• Author SOPs, study plans, reports, and present findings to teams and leadership.
• Collaborate with cross-functional teams for in vitro and in vivo experiments on biodistribution, safety and efficacy.
• Foster external collaborations and stay abreast of LNP trends, proposing new approaches.

Conocimientos

LNP characterization

Analytical methods development

Strong communication

Independent multitasking

Educación

Undergraduate or master's degree in biochemistry, chemical engineering, materials science, or related field

Herramientas

BLA

CBQCA

DLS

UPLC

HPLC-CAD

IP-RP HPLC

LC-MS/MS

CGE

BLI/SPR

ELISA

ddPCR/qPCR

Descripción del empleo

Stylus Medicine, Inc. is seeking an Associate Scientist to join our analytical development team, focusing on LNP characterization for in vivo genome delivery.

You will drive development of analytical techniques and provide support to the delivery team, reporting to the Principal Scientist, LNP Analytics. You will collaborate with cross-functional teams on in vitro and in vivo studies, contribute to SOPs and study plans, and help advance transformative in vivo genetic medicines from discovery