LNP Formulation Scientist II

eTeam; San Diego (CA); On-site; USD 90,000 - 130,000; Full time

Benefits offered by this job

Competitive salary

Job summary

eTeam in San Diego, CA, is seeking a motivated Scientist II to join the Formulation team to advance lipid nanoparticle (LNP) formulation for nucleic acid delivery. You will work with senior scientists on in vitro and in vivo studies, supporting non-viral delivery platforms and scale-up readiness.

You will design experiments, optimize LNPs, analyze data, maintain records, and collaborate across functions in a fast-paced lab environment.

Qualifications

• Bachelor's degree in Chemistry, Biochemistry, Chemical Engineering, or related discipline with 5 years in biopharma; OR
• Master's degree with 2 years of industry experience.
• Minimum 2 years of hands-on laboratory experience in LNP formulation and nucleic acid encapsulation.
• Experience with mRNA, siRNA, or DNA.
• Proficiency in LNP characterization techniques, including DLS and zeta potential.
• Strong attention to detail and ability to generate reproducible data.
• Excellent organizational, communication, and teamwork skills.
• Ability to work effectively in a fast-paced lab environment.

Responsibilities

• Formulate and optimize LNPs and targeted LNPs (tLNPs) encapsulating nucleic acids.
• Execute DoE screening campaigns to identify optimal LNP compositions and processing parameters.
• Characterize LNPs using DLS, zeta potential, and RiboGreen assays.
• Support early-stage formulation development, cryoprotection, scale-up, and stability studies.
• Collaborate with cross-functional teams to fulfill formulation requests.
• Maintain detailed lab records documenting formulation activities and results.
• Analyze, interpret, and present data to the formulation team.
• Assist routine lab operations including inventory, buffers, and autoclaving.

Skills

LNP Formulation

Nucleic Acid Encapsulation

DoE

DLS

RiboGreen

Excel

Data Analysis

Documentation

Teamwork

Education

BSc in Chemistry/Biochemistry

MSc in related field

Tools

JMP

GraphPad Prism

Job description

eTeam in San Diego, CA, is seeking a motivated Scientist II to join the Formulation team to advance lipid nanoparticle (LNP) formulation for nucleic acid delivery. You will work with senior scientists on in vitro and in vivo studies, supporting non-viral delivery platforms and scale-up readiness.

You will design experiments, optimize LNPs, analyze data, maintain records, and collaborate across functions in a fast-paced lab environment.