Lead Metabolomics Scientist - LC-MS/Lipidomics

Advancing People Ltd.; New York (NY); On-site; GBP 113,000 - 151,000; Full time

Job summary

Advancing People Ltd. is seeking an experienced Senior Scientist in metabolomics/lipidomics with hands-on LC-MS expertise to lead end-to-end workflows from sample prep to data reporting.

You will operate and troubleshoot industry-grade LC-MS systems, develop innovative detection methods, and collaborate across functions to deliver timely results in support of biopharmaceutical research. A PhD or MS with extensive post-grad experience is preferred.

Qualifications

• PhD with 2+ years post-graduation or MSc with 5+ years experience.
• Strong experience in targeted metabolomics LC-MS method development, validation and troubleshooting.
• Proficiency with AB SCIEX QTRAP 6500, Thermo Q Exactive Plus, and triple quad mass spectrometers.
• In-depth knowledge of LC-MS assay validation guidelines and GLP documentation requirements.
• Experience in metabolite identification/spectral analysis and small molecule quantification.
• Proficiency in sample pretreatment techniques and LC separation methods.
• Excellent scientific communication and ability to manage multiple projects.

Responsibilities

• Lead end-to-end implementation of LC-MS metabolomics/lipidomics workflows from sample prep to data analysis and reporting.
• Operate, maintain, and troubleshoot LC-MS systems and instruments.
• Design and implement innovative LC-MS/MS methods for complex matrices and sensitive analyses.
• Draft and follow SOPs; contribute to validation protocols and GLP documentation.
• Collaborate with cross-functional teams to define study scope, timelines, and risks.
• Support instrument validation and inventory management of standards and reagents.
• Mentor junior scientists and promote safety, quality, and continuous improvement.
• Stay current with metabolomics/lipidomics literature and introduce relevant advancements.

Skills

Metabolomics expertise

Lipidomics expertise

Analytical chemistry

Data interpretation

Scientific communication

Education

PhD in Analytical Chemistry or Biochemistry

Master's with 5+ years experience

Tools

AB SCIEX QTRAP 6500

Thermo Q Exactive Plus

Triple quadrupole MS

LC-MS systems

Job description

Advancing People Ltd. is seeking an experienced Senior Scientist in metabolomics/lipidomics with hands-on LC-MS expertise to lead end-to-end workflows from sample prep to data reporting.

You will operate and troubleshoot industry-grade LC-MS systems, develop innovative detection methods, and collaborate across functions to deliver timely results in support of biopharmaceutical research. A PhD or MS with extensive post-grad experience is preferred.