Lead Analytics Scientist - Proteins & Biotech

Helaina; New York (NY); On-site; USD 110,000 - 160,000; Full time

Benefits offered by this job

Medical coverage

Vision coverage

Dental coverage

Disability insurance

401k match

Unlimited vacation

Parental leave

Commuter benefits

Job summary

Helaina, a leading nutrition biotech company in NYC, is seeking a senior analytical chemist to design, validate, and troubleshoot experiments for the Analytics team and lead day-to-day delivery. This lab-based, on-site role offers high impact in a startup environment focused on bioactive proteins.

You will develop analytical workflows for recombinant proteins, manage equipment like UHPLC and MS systems, and collaborate across R&D to support product characterization and regulatory efforts.

Qualifications

• PhD/MS/BS in analytical chemistry or related field with 10+ years in-lab experience in biotech/academic setting.
• Deep knowledge of analytical techniques for protein purification and analysis (RP, IEX, SEC, HILIC).
• Mass-spectrometry characterization of proteins, including intact protein measurement and peptide mapping.
• Experience developing and validating proteomics and metabolomics workflows.
• Experience analyzing MS data with Skyline, Spectronaut, MaxQuant, UniDec preferred.
• Strong communicator within a collaborative scientific team and able to translate science for non-technical audiences.
• Bonus: experience with recombinant-protein purification/analysis; publications/patents/SOPs/regulatory filings.

Responsibilities

• Lead development and validation of analytical methods for recombinant proteins and food ingredients using HPLC, LC-MS, SDS-PAGE.
• Provide analytical support to R&D on strain engineering and process development for expression and production of recombinant proteins.
• Support product characterization across food applications for client requests.
• Operate major equipment (UHPLC and MS systems) and manage daily lab operations.
• Conduct method development, transfer, validation, and release/stability studies for ingredients and finished products.
• Collaborate with CROs/CMOs/CDMOs to advance company milestones.
• Support regulatory filings and quality impact assessments.
• Analyze, interpret, and present data to internal and external audiences.
• Plan and execute projects at team level, escalating risks and upholding quality standards.

Skills

Analytical chemistry

Mass spectrometry

Protein purification

Chromatography

Data interpretation

Scientific communication

Team leadership

Education

PhD/MS/BS in analytical chemistry or related field

Tools

HPLC

LC-MS

SDS-PAGE

Western blotting

Skyline

Spectronaut

MaxQuant

UniDec

Job description

Helaina, a leading nutrition biotech company in NYC, is seeking a senior analytical chemist to design, validate, and troubleshoot experiments for the Analytics team and lead day-to-day delivery. This lab-based, on-site role offers high impact in a startup environment focused on bioactive proteins.

You will develop analytical workflows for recombinant proteins, manage equipment like UHPLC and MS systems, and collaborate across R&D to support product characterization and regulatory efforts.