In Vivo Gene Insertion Scientist II

CRISPR Therapeutics; San Francisco (CA); On-site; USD 130,000 - 140,000; Full time

Benefits offered by this job

Bonus

Equity

Benefits

Job summary

CRISPR Therapeutics seeks highly motivated scientists to advance in vivo gene editing therapies. You will work on developing and enabling gene insertion across tissue types, using diverse editing systems and immunology knowledge.

The role requires adaptability, attention to detail, and collaboration across departments to push toward clinical readiness. The position focuses on hands-on molecular biology, ddPCR, flow cytometry, and data analysis, with a strong emphasis on team-based problem

Qualifications

• Extensive experience with gene editing and synthetic immunology in academic/industry settings.
• Excellent technical skills for cloning, flow cytometry, primary T cell culturing, editing assays, and T cell phenotype/function assessment.
• Experience managing multiple projects and priorities; able to jump in to help other projects as needed.
• Strong communicator with a collaborative, cross-departmental approach.

Responsibilities

• Design and execute workflows for conceive, build, and assess in primary cells with hands-on molecular biology.
• Design and execute ddPCR assays to quantify transgene integration efficiency.
• Design and execute T cell phenotyping assays using multicolor flow cytometry panels.
• Leverage immunology background to drive editing, delivery, and expression strategies.
• Collaborate cross-functionally to assess editing outcomes in animal models and present data.

Skills

Gene editing

Synthetic immunology

Flow cytometry

T cell culture

Cloning

Data analysis

Education

PhD in Biology/Immunology/Bioengineering

Experience equivalent without PhD (10-12+ years)

Tools

ddPCR

Flow cytometry

Job description

CRISPR Therapeutics seeks highly motivated scientists to advance in vivo gene editing therapies. You will work on developing and enabling gene insertion across tissue types, using diverse editing systems and immunology knowledge.

The role requires adaptability, attention to detail, and collaboration across departments to push toward clinical readiness. The position focuses on hands-on molecular biology, ddPCR, flow cytometry, and data analysis, with a strong emphasis on team-based problem