Biotherapeutics Downstream Scientist

Johnson Johnson; Malvern (Chester County); On-site; USD 90,000 - 120,000; Full time

Job summary

Johnson & Johnson in Malvern, PA, seeks an Associate Scientist in Downstream Processing to support biologics purification process development within the Protein Therapeutics API Development group. You will assist in bench-scale experiments, focusing on chromatography and filtration, to advance early-phase programs for biotherapeutics.

The role requires collaboration with upstream, analytical, formulation, and manufacturing teams, strong documentation, and adherence to cGxP and EHSS policies.

Qualifications

• B.S. or M.S. in a related discipline with relevant experience.
• Familiarity with protein purification, bioprocessing, or related methods.
• Basic understanding of experimental design and analysis.
• Self-motivated, eager to learn, and well organized.
• Strong written and verbal communication skills.
• Proficiency with MS Office (Excel, Word, PowerPoint).

Responsibilities

• Define work packages and purification development strategies for NME candidates.
• Execute chromatography and filtration experiments focusing on product quality.
• Assist in process characterization, scale-up, and technology transfer.
• Collaborate cross-functionally with upstream, analytical, formulation, and manufacturing teams.
• Author and review technical or regulatory documents.
• Maintain accurate records and comply with EHSS policies.
• Capture data accurately and maintain compliant records.

Skills

Protein purification

Bioprocessing

Experimental design

MS Office

Education

B.S. in Chemical Engineering/Biochemistry/Biotechnology

M.S. in Chemical Engineering/Biochemistry/Biotechnology

Tools

AKTA FPLC

JMP

Minitab

Job description

Johnson & Johnson in Malvern, PA, seeks an Associate Scientist in Downstream Processing to support biologics purification process development within the Protein Therapeutics API Development group. You will assist in bench-scale experiments, focusing on chromatography and filtration, to advance early-phase programs for biotherapeutics.

The role requires collaboration with upstream, analytical, formulation, and manufacturing teams, strong documentation, and adherence to cGxP and EHSS policies.