Downstream Purification Scientist (Biologics)

6084-Janssen Research & Development, LLC Legal Entity; Malvern (Chester County); On-site; USD 75,000 - 105,000; Full time

Job summary

Johnson & Johnson in Malvern, PA, is seeking an Associate Scientist, Downstream Processing, to support purification development for biotherapeutics in early-phase projects. The role emphasizes chromatography and filtration, bench-scale experiments, and rigorous documentation to meet program timelines.

You will collaborate with upstream, analytical, and formulation teams to drive process characterization, scale-up, and technology transfer, while ensuring data integrity and EHSS compliance.

Qualifications

• BS or MS in Chemical Engineering, Biochemistry, Biotechnology, or related field.
• 0–5 years for BS; 0–3 years for MS experience in protein purification/bioprocessing.

Responsibilities

• Define work packages and purification strategies for NME candidates in early-phase clinical manufacturing.
• Execute chromatography and filtration experiments focusing on product quality and recovery.
• Assist in process characterization, scale-up, and technology transfer of downstream operations.
• Collaborate cross-functionally with upstream, analytical, formulation, and manufacturing teams to meet program timelines.
• Author and review technical or regulatory documents; maintain compliant records.

Skills

Analytical reasoning

Collaboration

Problem solving

Written expression

Self-motivated

Education

BS in Chemical Engineering/Biochemistry/Biotechnology or related

MS in Chemical Engineering/Biochemistry/Biotechnology or related

Tools

MS Office

Akta FPLC

Job description

Johnson & Johnson in Malvern, PA, is seeking an Associate Scientist, Downstream Processing, to support purification development for biotherapeutics in early-phase projects. The role emphasizes chromatography and filtration, bench-scale experiments, and rigorous documentation to meet program timelines.

You will collaborate with upstream, analytical, and formulation teams to drive process characterization, scale-up, and technology transfer, while ensuring data integrity and EHSS compliance.