Bioanalysis Scientist II — LC-MS PK & Biomarkers

CRYSTAL PHARMATECH INC; Pleasanton (CA); On-site; USD 80,000 - 95,000; Full time

Job summary

Crystal Bio Solutions in Pleasanton, CA is seeking a Bioanalysis professional to provide PK and biomarker support across pre-clinical and clinical projects. You will perform LCMS analyses, validate assays, and ensure GLP/GCLP compliance while collaborating with client teams.

You will operate Sciex Triple Quadrupole systems, generate reports, and assist in qPCR, Flow Cytometry, and ADA-related efforts as needed. A strong background in analytical chemistry and timely delivery is required.

Qualifications

• Bachelor’s degree in Analytical Chemistry, Biochemistry or related field.
• 1+ year CRO/Pharma/Biotech experience for Associate Scientist II, or 3+ years for Sr. Associate Scientist.
• Experience with quantitative LCMS methodologies using Triple Quadrupole platforms.
• Hands-on GLP/GCLP regulated laboratory experience.
• Strong writing and communication skills; ability to meet timelines.

Responsibilities

• Perform PK and Biomarker sample analysis using validated LCMS assays with minimal supervision.
• Validate LCMS assays per SOPs and ICH M10 standards.
• Manage validation and analysis activities using Watson LIMS.
• Maintain GLP/GCLP compliance across method validation and analysis.
• Operate Sciex Triple Quadrupole platforms independently.
• Identify and escalate data quality issues in LCMS results.
• Author reports covering laboratory responsibilities for projects.
• Support qPCR, Flow Cytometry, LBA PK, and ADA efforts as needed.

Skills

LCMS

GLP/GCLP experience

Team collaboration

Written communication

Education

Bachelor’s degree in Analytical Chemistry, Biochemistry or related field

Tools

Watson LIMS

QMS systems

Sciex Triple Quadrupole

PCR

Flow Cytometry

Job description

Crystal Bio Solutions in Pleasanton, CA is seeking a Bioanalysis professional to provide PK and biomarker support across pre-clinical and clinical projects. You will perform LCMS analyses, validate assays, and ensure GLP/GCLP compliance while collaborating with client teams.

You will operate Sciex Triple Quadrupole systems, generate reports, and assist in qPCR, Flow Cytometry, and ADA-related efforts as needed. A strong background in analytical chemistry and timely delivery is required.