Senior Scientist, Preclinical Bioanalysis
This is an onsite position in the East Bay.
Provides bioanalytical support for biologics programs, with a focus on LC-MS–based assays for antibody-drug conjugates (ADCs) and related modalities.
Responsibilities:
- Design and execute LC-MS bioanalytical assays for biologics in rodent and NHP matrices
- Analyze PK samples and support studies from discovery through lead selection
- Manage and interpret PK studies (in-house and CRO)
- Perform data analysis and clearly communicate findings to cross-functional teams
- Collaborate across functions to support program advancement
- Contribute to translational biology efforts and ensure compliance with lab and safety standards
- Oversee work conducted by CROs or external partners
Qualifications:
- MS (7+ years) or PhD (2+ years) in analytical chemistry, biology, or related field
- Strong hands-on experience with LC-MS bioanalysis for biologics
- Solid understanding of PK/PD and preclinical pharmacology (oncology preferred)
- Experience with assay development; ligand-binding assays and metabolite ID a plus
- Strong analytical thinking, communication, and organizational skills
- Proficiency with standard scientific software (e.g., GraphPad, Excel)
Additional:
- Lab-based role with some exposure to hazardous materials