LC-MS/MS Bioanalytical Scientist — Small Molecules

Amgen Inc. (IR); Thousand Oaks (CA); On-site; USD 109,000 - 147,000; Full time

Job summary

Amgen Inc. seeks a Scientist LC-MS/MS Bioanalytical to design, validate, and implement quantitative LC-MS/MS methods for small molecules. The role supports discovery, GLP preclinical and regulated clinical studies, with cross-functional collaboration across R&D and regulatory teams.

The candidate will generate results for publications or regulatory submissions, review data, and mentor others in a fast-paced lab environment. Strong MS expertise on QQQ platforms is essential.

Qualifications

• PhD/PharmD/MD or MSc with LC-MS/MS experience.
• Experience in pharma/biotech preferred.
• Knowledge of regulatory expectations for bioanalysis.

Responsibilities

• Develop and implement LC-MS/MS bioanalytical methods with quick turnaround.
• Conduct small molecule bioanalysis in various matrices (plasma, urine, CSF, tissues).
• Perform sample extraction using SPE, LLE; ensure regulatory-compliant documentation.
• Generate study reports and analytical methods; support publications/regulatory submissions.
• Communicate data to discovery and development teams; present at meetings.
• Maintain training records; ensure safety and SOP compliance.

Skills

LC-MS/MS bioanalytical expertise

Project collaboration

Scientific data interpretation

Education

PhD/PharmD/MD

Master’s + 3 years LC-MS/MS

Bachelor’s + 5 years LC-MS/MS

Tools

SPE

LLE

LIMS

Electronic lab notebook

Job description

Amgen Inc. seeks a Scientist LC-MS/MS Bioanalytical to design, validate, and implement quantitative LC-MS/MS methods for small molecules. The role supports discovery, GLP preclinical and regulated clinical studies, with cross-functional collaboration across R&D and regulatory teams.

The candidate will generate results for publications or regulatory submissions, review data, and mentor others in a fast-paced lab environment. Strong MS expertise on QQQ platforms is essential.