Associate Scientist, Translational Immunology & Flow Cytometry

Lila Sciences, Inc.; Cambridge (MA); On-site; USD 88,000 - 144,000; Full time

Benefits offered by this job

Medical, dental, and vision benefits

Equity opportunities

Generous holidays and PTO

Commuter benefits

Company lunch program

Job summary

Lila Sciences, Inc. is seeking an Associate Scientist with deep flow cytometry and cross-species tissue handling expertise to join our translational biology team.

You will independently isolate and process cells from liver, spleen, and whole blood across multiple species and run high-dimensional panels to evaluate LNP delivery and immune activation. You will mentor juniors and help shape high-throughput workflows.

Qualifications

• BS with 5+ years or MS with 3+ years of hands-on laboratory experience in Biology, Biochemistry, Immunology, Biomedical Engineering, or a related life science field; industry experience preferred.
• Advanced, demonstrated expertise in multi-parameter flow cytometry with high-dimensional panel design, fluorophore selection, compensation/unmixing, and data interpretation.
• Experience with FlowJo and multi-parameter data analysis; experience with spectral or high-parameter platforms preferred.
• Ex vivo tissue processing and cell isolation across mouse, rat, NHP, and human samples; cross-species workflows experience.

Responsibilities

• Execute high-dimensional flow cytometry panels to assess viability, LNP uptake, and immune markers.
• Oversee full flow workflow: fluorophore selection, compensation, instrument QC, acquisition, and data analysis.
• Isolate viable single-cell suspensions across species; perform tissue processing and PBMC isolation.
• Prepare tissues from in vitro/in vivo studies for flow, ELISA, multiplex, and qPCR analyses.
• Drive readouts for LNP delivery across species and tissues; translate data into actionable insights.
• Conduct high-throughput flow-based screening and assist automation team in design.
• Maintain biorepository integrity and robust sample tracking across studies.
• Assist with multiplex immunoassays (MSD, Luminex, ELLA) and SOP development.

Skills

Flow cytometry

Multi-parameter panels

Ex vivo tissue processing

Cross-species samples

Data analysis & interpretation

Experiment design

Mentoring junior scientists

FlowJo proficiency

Education

BS or MS in Biology/Immunology

Tools

FlowJo

FACS

Spectral flow cytometry

Job description

Lila Sciences, Inc. is seeking an Associate Scientist with deep flow cytometry and cross-species tissue handling expertise to join our translational biology team.

You will independently isolate and process cells from liver, spleen, and whole blood across multiple species and run high-dimensional panels to evaluate LNP delivery and immune activation. You will mentor juniors and help shape high-throughput workflows.