Associate Scientist, Immunology & Target Validation

Flagship Pioneering, Inc.; Cambridge (MA); On-site; USD 96,000 - 127,000; Full time

Job summary

Quotient Therapeutics is seeking an Associate Scientist with experience in molecular biology, immunology, and early drug discovery to advance translational validation in inflammatory and autoimmune disease models.

The role involves designing in vitro assays, executing cell-based and biochemical experiments, and interpreting data to guide go/no-go decisions within a dynamic, cross-functional team.

Qualifications

• BS or MS in Immunology, Biochemistry, Molecular Biology, or a related discipline with 3+ years of industry experience for MS or 5+ years for BS.
• In-depth understanding of cellular and molecular biology techniques including mammalian cell culture, transfection, CRISPR, western blots, qPCR, immunofluorescence and flow cytometry.
• Prior experience running cell-based compound screening assays.
• Prior experience in an industrial setting, and familiarity with GLP as well as proficiency in ELN.
• Experience with experimental design and strong proficiency in assay execution, troubleshooting, data analysis, and data interpretation.
• Outstanding organizational and record keeping skills.
• Execution focused, team oriented, and highly motivated.

Responsibilities

• Design, optimize and implement robust in vitro experiments to validate target mechanisms and translational relevance to human disease.
• Execute biochemical and cell-based assays using recombinant proteins, mammalian cell lines and primary cells to define drug mechanism of action.
• Innovate, troubleshoot and interpret data to drive go/no go decisions.
• Maintain precise experimental records and documentation.
• Contribute to preparation of research articles, reports and presentations.
• Follow lab safety procedures and participate in regular team meetings.

Skills

Mammalian cell culture

Transfection

CRISPR

Western blot

qPCR

Immunofluorescence

Flow cytometry

Cell-based screening assays

Data analysis

Research design

Education

BS/MS in Immunology, Biochemistry or Molecular Biology

Tools

ELN

Job description

Quotient Therapeutics is seeking an Associate Scientist with experience in molecular biology, immunology, and early drug discovery to advance translational validation in inflammatory and autoimmune disease models.

The role involves designing in vitro assays, executing cell-based and biochemical experiments, and interpreting data to guide go/no-go decisions within a dynamic, cross-functional team.