AI-Enabled Life Sciences Manufacturing Transformation Leader

EY; Denver (CO); Remote; USD 150,000 - 344,000; Full time

Benefits offered by this job

Medical and dental coverage

Pension and 401(k)

Paid time off

Job summary

EY is seeking a Senior Manager in Supply Chain Manufacturing to lead life sciences manufacturing transformations, connecting plant operations with enterprise systems and data. You will drive end-to-end programs across manufacturing, quality, engineering, and IT/OT, shaping processes and data models, and delivering measurable improvements in regulated environments.

You will manage teams delivering MES/MOM, automation, data engineering, AI, and analytics, ensuring governance, risk management, and

Qualifications

• Bachelor’s degree in engineering, life sciences, manufacturing, supply chain, information systems, business, or related discipline.
• 10+ years of relevant experience spanning Life Sciences manufacturing, manufacturing technology, operational excellence, industrial data and AI, technology consulting, or related field.
• Experience leading complex manufacturing transformation or technology-enabled improvement initiatives in regulated environments.
• Experience delivering client-facing programs through design, implementation, deployment, and stabilization with governance, resources, quality, and risk accountability.
• Experience leading senior stakeholders and multidisciplinary teams across business, functional, data, and technology workstreams.

Responsibilities

• Lead end-to-end Life Sciences manufacturing transformations from assessment to value realization.
• Build trusted relationships with senior stakeholders; establish governance and drive decisions.
• Translate priorities into practical workplans and outcome measures.
• Direct multidisciplinary teams across design, automation, data engineering, AI, and integration.
• Guide integration across MES/MOM, ERP, LIMS, QMS, historians, and OT/IT systems.
• Establish trusted manufacturing data foundations with proper governance and lineage.
• Shape analytics and AI use cases; assess data readiness and risks before scaling.
• Partner with quality and validation teams to incorporate GxP controls and data integrity.

Skills

Techno-functional leadership

Industrial data

OPC UA

AI in manufacturing

Executive communication

Delivery discipline

Education

Bachelor's degree in engineering

Tools

MES/MOM

eBRs

eDHRs

Recipe management

Job description

EY is seeking a Senior Manager in Supply Chain Manufacturing to lead life sciences manufacturing transformations, connecting plant operations with enterprise systems and data. You will drive end-to-end programs across manufacturing, quality, engineering, and IT/OT, shaping processes and data models, and delivering measurable improvements in regulated environments.

You will manage teams delivering MES/MOM, automation, data engineering, AI, and analytics, ensuring governance, risk management, and