ADC Process Engineer - Scale-Up & Kinetics Lead

BioSpace; North Chicago (IL); On-site; USD 150,000 - 210,000; Full time

Job summary

AbbVie in the United States is seeking an experienced R&D Process Engineer to design and scale manufacturing processes for small molecules and ADCs. You will lead cross-functional teams, develop robust processes, and contribute to regulatory filings.

The role emphasizes modeling ADC kinetics, drug linker/process design, and implementing innovative reactor configurations to enable scalable, compliant manufacturing.

Qualifications

• BS/MS/PhD in Chemical/Bio Engineering or related field with industrial experience.
• Demonstrated capability to model ADC kinetics and mechanisms.
• Experience with drug linker and drug substance process design, including tech transfer and scale-up.
• Development of flow chemistry reactor platforms used for ADCs.

Responsibilities

• Develop robust manufacturing processes through all development phases.
• Lead teams to develop and characterize new small and large molecule assets.
• Create commercial-ready manufacturing processes in lab and pilot plant.
• Set project strategies, timelines, and provide leadership in a matrixed team.
• Address complex reaction problems using kinetics, transport phenomena, and modeling.
• Apply process analytical technologies and data-rich experimentation to build understanding.

Skills

ADC kinetics modeling

Flow chemistry

Highly potent handling

Reactor configuration development

Computational fluid dynamics

Team leadership

Oral and written communication

Education

BS in Chemical/Bio Engineering

MS in Chemical/Bio Engineering

PhD in Chemical/Bio Engineering

Tools

Tech transfer processes

Process analytical technologies

CFD software

Job description

AbbVie in the United States is seeking an experienced R&D Process Engineer to design and scale manufacturing processes for small molecules and ADCs. You will lead cross-functional teams, develop robust processes, and contribute to regulatory filings.

The role emphasizes modeling ADC kinetics, drug linker/process design, and implementing innovative reactor configurations to enable scalable, compliant manufacturing.