Postdoctoral Fellow in Molecular Cell Biology (ref 307897)

EuroSoHo; Oslo; Hybrid; NOK 520,000 - 600,000; Full time

Job summary

University of Oslo is seeking a highly motivated postdoctoral researcher to investigate ER-phagy and its role in cancer progression. The candidate will perform molecular biology experiments, gene editing with CRISPR/Cas9, protein analysis, and advanced imaging to elucidate regulatory mechanisms.

The project requires independent work, strong collaboration, and the ability to interpret complex data. Experience in autophagy or intracellular trafficking is advantageous and supervision of students

Qualifications

• Extensive laboratory experience in molecular cell biology.
• Experience with CRISPR/Cas9 genome editing.
• Proficiency in cell culture, microscopy, and protein analysis.

Responsibilities

• Carry out the ER-phagy project within the allocated timeframe.
• Interpret and communicate research results clearly.
• Possibility to supervise students during the project.

Skills

Molecular biology

CRISPR/Cas9

Cell culture

Microscopy

Protein analysis

Education

PhD in Molecular/Cell Biology

Tools

Light microscopy

Protein expression

Job description

Organisation/Company University of Oslo Research Field Medical sciences Researcher Profile Recognised Researcher (R2) Positions Postdoc Positions Application Deadline 13 Oct 2026 - 23:00 (Europe/Oslo) Country Norway Type of Contract Temporary Job Status Full-time Hours Per Week 37.5 Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No

Offer Description

Most cancer cells exhibit persistent endoplasmic reticulum stress, which promotes tumour growth, metastasis and resistance to therapies. Stressed endoplasmic reticulum is cleared by a pathway known as "ER-phagy", yet it remains unclear how ER-phagy dysregulation contributes to cancer progression. Using image-based siRNA screens, we have identified novel regulators of ER-phagy. This project aims to investigate the molecular mechanisms of ER-phagy and how this contributes to cancer progression.

The successful candidate should have extensive experience from experimental laboratory work in molecular cell biology using techniques such as cell culture, CRISPR/Cas9 based genome editing, protein expression and interaction analysis, light microscopy and/or cancer assays. Prior experience in the autophagy or intracellular trafficking fields is considered an advantage.

We are looking for a highly motivated individual with the ability to work in an accurate and structured manner to carry out the project within the given timeframe. The candidate should be able to work both independently and collaboratively, and be able to effectively interpret and communicate research results. The candidate may also have the opportunity to supervise students.