Postdoctoral Fellow in Molecular Cell Biology (ref 307897)

Euraxess; Oslo; Hybrid; NOK 550,000 - 650,000; Full time

Job summary

University of Oslo invites applications for a Postdoctoral Researcher position focusing on ER-phagy and cancer progression, aiming to uncover molecular mechanisms driving tumor biology.

Applicants should have hands-on experience with cell culture, CRISPR/Cas9 genome editing, protein analysis, and microscopy; autophagy knowledge is a plus. Independence, collaboration, and clear data interpretation are essential.

Qualifications

• Experience in experimental laboratory work in molecular cell biology.
• Experience with CRISPR/Cas9 genome editing.
• Ability to work independently and collaboratively; communicate results.

Responsibilities

• Investigate ER-phagy mechanisms and cancer progression.
• Perform cell culture, CRISPR edits, protein analysis, and microscopy.
• Collaborate with team and possibly supervise students.

Skills

CRISPR/Cas9

Cell culture

Microscopy

Protein analysis

Autophagy knowledge

Job description

Organisation/Company University of Oslo Research Field Medical sciences Researcher Profile Recognised Researcher (R2) Positions Postdoc Positions Application Deadline 13 Oct 2026 - 23:00 (Europe/Oslo) Country Norway Type of Contract Temporary Job Status Full-time Hours Per Week 37.5 Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No

Offer Description

Most cancer cells exhibit persistent endoplasmic reticulum stress, which promotes tumour growth, metastasis and resistance to therapies. Stressed endoplasmic reticulum is cleared by a pathway known as "ER-phagy", yet it remains unclear how ER-phagy dysregulation contributes to cancer progression. Using image-based siRNA screens, we have identified novel regulators of ER-phagy. This project aims to investigate the molecular mechanisms of ER-phagy and how this contributes to cancer progression.

The successful candidate should have extensive experience from experimental laboratory work in molecular cell biology using techniques such as cell culture, CRISPR/Cas9 based genome editing, protein expression and interaction analysis, light microscopy and/or cancer assays. Prior experience in the autophagy or intracellular trafficking fields is considered an advantage.

We are looking for a highly motivated individual with the ability to work in an accurate and structured manner to carry out the project within the given timeframe. The candidate should be able to work both independently and collaboratively, and be able to effectively interpret and communicate research results. The candidate may also have the opportunity to supervise students.