Postdoc: Antibody Characterization & Wet-Lab Validation

BioMed X AG; Paris; Sur place; EUR 42 000 - 54 000; Plein temps

Avantages offerts par ce poste

Mentoring and training

Résumé du poste

BioMed X is seeking a Postdoctoral Researcher to build and lead the wet-lab characterization arm of our AI-guided bispecific antibody discovery program. You will join a team blending computational structural biology, machine learning, and antibody engineering to design next-generation bispecifics.

Based at BioMed X in France, you will contribute to experimental design, data integrity, and close collaboration with Servier on a high-profile XSeed Labs project, with mentoring from senior scientists

Qualifications

• PhD in Structural Biology, Life Sciences, Biochemistry, or a closely related field.
• Hands-on expertise in protein expression/purification, thermostability assays, and characterisation of protein–antibody complexes (BLI/SPR, BRET/FRET, X-ray/cryo-EM).
• Track record of independent project management, able to own a workstream end to end.
• Publication record demonstrating research rigor and output.
• Strong oral and written communication skills.

Responsabilités

• Set up and run the lab's core characterisation pipeline with our biological engineer: protein expression and purification, thermostability assays, and standard PPI binding assays.
• Design experiments and assays to test hypotheses generated by the team, and help pinpoint why designs succeed or fail.
• Own wet-lab data integrity, traceability, and the consolidation of experimental and computational datasets.
• Manage CRO relationships where external capacity is needed (e.g., protein production, specialised assays).
• Work closely with computational scientists to close the design-test-learn loop.

Connaissances

Protein expression/purification

Thermostability assays

Characterisation of protein–antibody–A

Project management

Publication track record

Communication skills

Formation

PhD in Structural Biology, Life Sciences, Biochemistry, or closely related field

Description du poste

BioMed X is seeking a Postdoctoral Researcher to build and lead the wet-lab characterization arm of our AI-guided bispecific antibody discovery program. You will join a team blending computational structural biology, machine learning, and antibody engineering to design next-generation bispecifics.

Based at BioMed X in France, you will contribute to experimental design, data integrity, and close collaboration with Servier on a high-profile XSeed Labs project, with mentoring from senior scientists