Senior Scientist – Biomarker R&D (m/f/d)

Incipiam; München; Hybrid; EUR 90,000 - 130,000; Full time

Job summary

Noselab in Munich is seeking a Senior Scientist to lead biomarker discovery, validation, and translational R&D across proteomics, immunoassays and emerging omics. You will design robust workflows, analyze complex biomarker data, and collaborate with pharma and academia to translate findings into actionable insights.

The role requires a PhD in life sciences, strong background in protein biomarkers, and experience shaping biomarker platforms with rigorous data interpretation and publication-style

Qualifications

• PhD or equivalent in life sciences with biomarker discovery experience.
• Experience translating findings into robust analytical or biological evidence.
• Strong expertise in protein biomarkers and assay development.
• Experience with LC-MS-based proteomics is a major plus.

Responsibilities

• Lead biomarker discovery, characterization and validation projects end-to-end.
• Design, optimize and apply bioanalytical methods for protein biomarkers.
• Work with complex samples and assess analytical performance and variability.
• Expand platform capabilities to other omics and nucleic acid methods.
• Integrate data from multiple platforms to identify promising biomarkers.
• Drive R&D projects with industry and academic partners; ensure timely, quality deliverables.
• Communicate results and contribute to publications, proposals and planning.
• Provide scientific guidance to colleagues and develop efficient workflows.

Skills

Biomarker discovery

Protein biomarkers

Bioanalytical methods

Proteomics

Data analysis

Experimental design

English proficiency

Education

PhD in Biochemistry/Molecular Biology/Biotech/Analytical Chemistry

Tools

LC-MS/MS

Immunoassays

Job description

Founded in May 2020, my client Noselab, based in Munich, Germany, focuses on a new, proprietary and groundbreaking platform for the detection, evaluation and characterization of molecular/protein biomarkers through the analysis of nasal fluid. This unique method is complemented by an innovative, data-driven medical approach that enables comprehensive biomarker profiling, improves the understanding of diseases and supports personalized treatment decisions.

We are looking for an experienced Senior Scientist with a strong background in industrial biomarker research and development.

Key responsibilities:

• Lead and execute biomarker discovery, characterization and validation projects, from experimental design through data analysis, interpretation and reporting.
• Design, optimize and apply bioanalytical methods for protein biomarker analysis including immunoassays, targeted and discovery-based proteomics, and other emerging technologies.
• Work with complex biological samples, develop robust sample preparation and pre- analytical workflows, and assess analytical performance, reproducibility and sources of variability.
• Drive the expansion of Noselab's biomarker platform beyond its current focus on proteins, evaluating the potential of complementary approaches such as other omics technologies, extracellular vesicle analysis and nucleic acid-based methods.
• Integrate and interpret data from different analytical platforms to identify promising biomarkers, evaluate their biological relevance, analytical robustness and support their translation into downstream applications.
• Drive internal R&D and collaborative projects with pharmaceutical, biotech and academic partners, ensuring scientific quality, timely execution and actionable deliverables
• Evaluate new technologies, analytical platforms and biomarker candidates to expand Noselab's technological capabilities and biomarker portfolio.
• Communicate scientific results to internal and external stakeholders and contribute to publications, presentations, application notes, grant proposals, patent applications, project outlines and strategic R&D planning.
• Provide scientific guidance to colleagues and contribute to the development of efficient, high-quality workflows.

Key Requirements:

• PhD or equivalent qualification in Biochemistry, Molecular Biology, Biotechnology, Analytical Chemistry or a related life science discipline.
• Demonstrated experience in biomarker discovery and development within the pharmaceutical or biotechnology industry, with a track record of independently driving research projects and translating scientific findings into robust analytical or biological evidence.
• Strong expertise in protein biomarkers and bioanalytical methods, including assay development, optimization and validation.
• Experience in proteomics is a major advantage, particularly LC-MS-based proteomics, affinity-based proteomic platforms or the integration of discovery proteomics with targeted biomarker validation.
• Strong experimental design, quantitative data analysis and critical interpretation skills, including the ability to assess analytical performance, biological variability, confounders and the robustness of biomarker findings.
• Experience working with complex biological matrices, such as plasma, serum, CSF, tissue or other biofluids, and an understanding of pre-analytical variables.
• Ability to work independently, prioritize competing project demands and communicate scientific findings effectively in an interdisciplinary environment.
• Excellent written and spoken English.
• Experience with other omics technologies, extracellular vesicles, cfDNA or emerging biomarker modalities is a plus, as is the ability to assess the potential of new technologies and translate them into practical R&D applications.

Preferred qualifications

• Experience/background in the field of neurodegenerative diseases or another field of neuroscience is a strong plus
• Experience in working in regulated environments (e.g. GCLP) and adhering to standards
• Additional experience in nucleic acid analysis, genomics and liquid biopsies

What We Offer:

• Direct impact on how cutting-edge diagnostics accelerate biopharma innovation A dynamic, collaborative and purpose-driven work culture
• A permanent full-time position with competitive salary and long-term career growth opportunities
• Flexible work setup with time on-site in Munich and home-office options