Senior Scientist (f/m/x) in Metabolomics and Tracer Analytics

Helmholtz Munich; München; Hybrid; EUR 90,000 - 120,000; Full time

Benefits offered by this job

30 days annual leave

Relocation support

International research environment

Job summary

Helmholtz Munich in Munich, Germany invites applications for a Senior Scientist (f/m/x) to build and grow tracer metabolomics and fluxomics capabilities within the Core Facility Metabolomics and Proteomics. You will lead method development, supervise staff, and guide researchers from study design to publication.

The role reports to the Head of the Core Facility and starts January 2027. A dynamic, international research environment and opportunities for collaboration are offered, along with

Qualifications

• PhD in Biochemistry, Analytical Chemistry, Systems Biology, or a related field.
• Demonstrated expertise in tracer metabolomics and/or metabolic flux analysis using 13C, 15N and/or deuterium-labelled substrates.
• Hands-on experience across the tracer workflow, from experimental design to data analysis and interpretation.
• Experience with LC-MS/MS and GC-MS/MS instrumentation, including operation, optimization and troubleshooting.
• Hands-on experience with mammalian cell culture and the processing of other relevant biological matrices (e.g., tissues, biofluids) for metabolomics analyses.
• Solid understanding of cellular metabolism and metabolic pathways, with the ability to interpret data in a biological context.
• Computational skills for metabolomics and fluxomics data analysis, including proficiency in R and/or Python.
• Experience with software such as El-MAVEN, XCMS, MetaboAnalyst, INCA or 13CFLUX2 (or comparable tools).
• Experience in training users, teaching, or supervising scientific or technical staff.
• Clear and engaging communication to internal and external audiences.
• Strong commitment to customer-oriented scientific service and collaborative research.

Responsibilities

• Design, establish and optimise a state-of-the-art stable isotope tracing and flux experiment services.
• Develop and apply data analysis workflows for stable isotope tracer experiments, isotopologue data analysis, and metabolic flux modeling.
• Perform and supervise metabolomics, lipidomics and fluxomics analyses using LC-MS/MS and GC-MS/MS platforms.
• Develop and maintain analytical methods, SOPs and quality-control procedures.
• Advise researchers on study design, tracer selection and experimental strategies.
• Support investigators in interpretation of results, publications and grant applications.
• Train and educate users in tracer metabolomics methodologies.
• Supervise and mentor scientific and technical staff supporting facility operations.

Skills

Tracer metabolomics

Metabolic flux analysis

LC-MS/MS

GC-MS/MS

Mammalian cell culture

R / Python

El-MAVEN

XCMS

MetaboAnalyst

INCA

13CFLUX2

Training users

Communication

Education

PhD in Biochemistry, Analytical Chemistry, Systems Biology, or a related field

Job description

At Helmholtz Munich, we develop groundbreaking solutions for a healthier society in a rapidly changing world. We believe that diverse perspectives drive innovation. Through strong partnerships, we accelerate the transfer of new ideas from the lab to real-life applications, improving lives.

We are looking to strengthen and expand the portfolio of functional omics services in our Core Facility Metabolomics and Proteomics and are seeking a highly motivated and accomplished Senior Scientist (f/m/x) to establish and expand tracer metabolomics and fluxomics capabilities, supporting researchers across Helmholtz Munich and beyond.

Our new colleague will be a team player enthusiastic about developing new analytical methods and advancing state-of-the-art metabolomics technologies. Training users, teaching advanced analytical methods, supervising scientific and technical staff and presenting results internally and externally are part of the job. The position reports directly to the Head of the Metabolomics and Proteomics Core Facility and will be available from January 2027.

Come and join a vibrant, cutting-edge international research environment and a highly motivated, collaborative Core Facilities team. We look forward to hearing from you.

• Design, establish and optimise a state-of-the-art stable isotope tracing and flux experiment services.
• Develop and apply data analysis workflows for stable isotope tracer experiments, isotopologue data analysis, and metabolic flux modeling.
• Perform and supervise metabolomics, lipidomics and fluxomics analyses using LC-MS/MS and GC-MS/MS platforms.
• Develop and maintain analytical methods, SOPs and quality-control procedures.
• Advise researchers on study design, tracer selection and experimental strategies.
• Support investigators in interpretation of results, publications and grant applications.
• Train and educate users in tracer metabolomics methodologies.
• Supervise and mentor scientific and technical staff supporting facility operations.

Your profile

• PhD in Biochemistry, Analytical Chemistry, Systems Biology, or a related field.
• Demonstrated expertise in tracer metabolomics and/or metabolic flux analysis using 13C, 15N and/or deuterium-labelled substrates.
• Hands-on experience across the tracer workflow, from experimental design to data analysis and interpretation.
• Experience with LC-MS/MS and GC-MS/MS instrumentation, including operation, optimization and troubleshooting.
• Hands-on experience with mammalian cell culture and the processing of other relevant biological matrices (e.g., tissues, biofluids) for metabolomics analyses.
• Solid understanding of cellular metabolism and metabolic pathways, with the ability to interpret data in a biological context.
• Computational skills for metabolomics and fluxomics data analysis, including proficiency in R and/or Python.
• Experience with software such as El-MAVEN, XCMS, MetaboAnalyst, INCA or 13CFLUX2 (or comparable tools).
• Experience in training users, teaching, or supervising scientific or technical staff.
• Clear and engaging communication to internal and external audiences.
• Strong commitment to customer-oriented scientific service and collaborative research.

If you fulfill all the requirements, you may be eligible for a salary grade of up to E 14. Social benefits are based on the Collective Wage Agreement for Public-Sector Employees (TVöD). The position has an (initial) fixed term of 2 years, with the possibility of moving to a permanent contract.

We offer

• The opportunity to build and shape a new strategic capability in tracer metabolomics and fluxomics.
• Access to state-of-the-art mass spectrometry infrastructure and large translational research programs.
• Close interaction with leading scientists in metabolic health, precision prevention, bioengineering and health AI.
• A highly collaborative and international research environment with extensive opportunities for scientific networking.
• Career Development: Postdoc program, scientific training & career center with tailored offers
• Scientific Resources: State-of-the-art infrastruture and Core Facilities
• Recreation: 30 days annual leave, flexi days, plus public holidays
• International Staff Service: Support with the relocation and integration process in Germany

We are committed to promoting a culture of diversity and welcome applications from talented people regardless of gender, cultural background, nationality, ethnicity, sexual identity, physical abilities, religion or age. In case of equal qualifications, preference will be given to applicants with severe disabilities.