Biomarker Development - Scientist

Actalent; Basel; On-site; CHF 130,000 - 180,000; Full time

Job summary

Actalent is seeking a Biomarker Development Scientist to drive exploratory biomarker strategies across the clinical pipeline. The role focuses on delivering innovative biomarker solutions through hands-on assay development and collaboration with internal teams and external providers.

Responsibilities include developing soluble biomarker assays (ELISA, MSD, NULISA, Ella) and LC-MS methods, interpreting data to support mechanism and dose selection, and ensuring timely, high-quality results across

Qualifications

• Degree in Biology, Immunology, or related field.
• 5+ years in pharma/biotech laboratory setting.
• Experience with ligand binding assays and LC-MS.

Responsibilities

• Develop and validate soluble biomarker assays focusing on ligand binding assays.
• Transfer, implement and monitor assay development at external providers.
• Generate and interpret biomarker data for mechanism and dose selection.
• Ensure quality and timely data delivery from internal and outsourced activities.

Skills

Biomarker development

Ligand binding assays

LC-MS

Regulatory knowledge

Translational science

Education

Biology degree

Tools

ELISA

MSD

NULISA

Ella

LC-MS

Job description

If you have hands-on laboratory experience on biomarker assays with special focus on ligand binding assays, this role might be perfect for you!

Our client is looking for a Biomarker Development Scientist to execute exploratory biomarker strategies across their clinical pipeline, and deliver innovative biomarker solutions.

Responsibilities

• Hands-on development and validation of soluble biomarker assays with special focus on ligand binding assays (ELISA, MSD, NULISA, and Ella), and other state of the art technologies including LC-MS
• Providing subject matter expertise for transferring, implementation and monitoring of soluble biomarker assay development, validation and sample analysis at external providers.
• Generate and interpret biomarker assay data to enable proof of mechanism, dose selection & proof of biology across early clinical programs and present results at internal meetings
• Ensuring quality and timely delivery of data generated through internal and outsourced biomarker assay activities.

Requirements

• Degree in Biology, Immunology, Cell Biology or equivalent field
• Experience as a laboratory technician with 5+ year in the pharmaceutical or biotechnology environment
• Practical experience in ligand binding assays and in LC-MS methods
• Understanding of regulatory requirement relevant to Biomarker Development (e.g. GCLP, ICH)
• Strong track record for providing scientific contributions in biomarkers, translational science, or analytical technologies

Please note that we can only consider EU/Schengen applications, or valid Swiss permit.